Yanfei Qi, PhD

Yanfei Qi, PhD
Assistant Professor of Medicine

Email: yanfei.qi@medicine.ufl.edu

TEL: 352.625.0820
FAX: 352.392.3606
ADMIN: 352.273.9308

 

 

 

 
Dr. Yanfei Qi Is an Assistant Professor of Medicine with the University of Florida’s Division of Cardiovascular Medicine.  In 2002, she received a Doctor of Medicine and in 2005, a Master of Science in Biochemistry, both from Guiyang Medical College in Guiyang, China.  Dr. Qi received her PhD in Pharmacodynamics in 2009 at the University of Florida.  In 2012, she was the recipient of the Annual High Blood Pressure Research Conference New Investigator award.  Additionally, Dr. Qi is a member of the American Heart Association and American Physiological Society.

Degree/Program

Institution

Field/Specialty

Doctor of Medicine Guiyang Medical College Medicine
Masters of Science Guiyang Medical College Biochemistry and Molecular Biology
PhD University of Florida Pharmacodynamics

Academic/Research Interests:

  • Dr. Qi’s major interest focuses on investigating the pathophysiology of cardiovascular diseases.  Specifically, Dr. Qi has been studying components of vasoprotective axis of the renin-angiotensin system and its role in hypertension, pulmonary hypertension, and ischemic heart failure.

Clinical Interests:

  • Dr. Qi’s is interested in stem cell therapy for cardiovascular diseases and studying the involvement of microbiome and neuroinflammation in patients with cardiovascular diseases.

Publications:

  • Qi Y, Katovich MJ. Is angiotensin II type 2 receptor a new therapeutic target for cardiovascular disease? Exp Physiol. 2014;99(7):933-4.
  • Qi Y and Raizada MK. Is Natriuretic Peptide Receptor C a New Target for Hypertension Therapeutics? Hypertension. 2014 Jan 27. [Epub ahead of print]
  • Qi Y, Zhang J, Cole-Jeffrey C, Shenoy V, Espejo A, Hanna M, Song C, Pepine C, Katovich MJ, and Raizada MK. Diminazene aceturate attenuates ischemia-induced cardiac pathophysiology. Hypertension. 2013;62(4):746-52.
  • Shan Z, Zubcevic J, Shi P, Jun JY, Dong Y, Murça TM, Lamont GJ, Cuadra A, Yuan W, Qi Y, Li Q, Paton JF, Katovich MJ, Sumners C, Raizada MK. Chronic Knockdown of the Nucleus of the Solitary Tract AT1 Receptors Increases Blood Inflammatory-Endothelial Progenitor Cell Ratio and Exacerbates Hypertension in the Spontaneously Hypertensive Rat. Hypertension. 2013; 61(6):1328-33.
  • Shenoy V, Gjymishka A, Jarajapu YP, Qi Y, Afzal A, Rigatto K, Ferreira AJ, Fraga-Silva RA, Kearns P, Douglas JY, Agarwal D, Mubarak KK, Bradford C, Kennedy WR, Jun JY, Rathinasabapathy A, Bruce E, Gupta D, Cardounel AJ, Mocco J, Patel JM, Francis J, Grant MB, Katovich MJ, Raizada MK. Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models. Am J Respir Crit Care Med. 2013;187(6):648-57.
  • Qi Y, Li Q, Shenoy V, Zingler M, Jun J, Verma A, et al. Comparison of transduction efficiency of tyrosine-mutant AAV serotype vectors in kidney. Clinical and Experimental Pharmacology and Physiology. 2013; 40(1):53-5.
  • Qi Y, Li H, Shenoy V, Li Q, Wong F, Zhang L, et al. Moderate cardiac-selective overexpression of angiotensin II type 2 receptor protects cardiac functions from ischaemic injury. Experimental Physiology. 2012;97(1):89-101.
  • Jun JY, Zubcevic J, Qi Y, Afzal A, Carvajal JM, Thinschmidt JS, et al. Brain-mediated dysregulation of the bone marrow activity in angiotensin II-induced hypertension. Hypertension. 2012; 60(5):1316-23.
  • Qi Y, Shenoy V, Wong F, Li H, Afzal A, Mocco J, Sumners C, Raizada MK, Katovich MJ. Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology. Experimental Physiology. 2011; 96(9): 863-74.
  • Shenoy V, Qi Y, Katovich MJ, Raizada MK. ACE2, a promising therapeutic target for pulmonary hypertension. Current Opinion in Pharmacology. 2011; 11(2):150-5.
  • Ferreira AJ, Shenoy V, Qi Y, Fraga-Silva RA, Santos RA, Katovich MJ, Raizada MK. Angiotensin-Converting Enzyme 2 Activation Protects Against Hypertension-Induced Cardiac Fibrosis Involving Extracellular Signal-Regulated Kinases. Experimental Physiology. 2010; 96(3):287-94.
  • Qi Y, Liu X, Li H, Shenoy V, Li Q, Hauswirth WW, Sumners C, Katovich MJ. Selective tropism of the recombinant adeno-associated virus 9 serotype for rat cardiac tissue. The Journal of Gene Medicine. 2010; 12(1):22-34.
  • Shenoy V, Ferreira AJ, Qi Y, Fraga-Silva RA, Díez-Freire C, Dooies A, Jun JY, Sriramula S, Mariappan N, Pourang D, Venugopal CS, Francis J, Reudelhuber T, Santos RA, Patel JM, Raizada MK, Katovich MJ. The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 2010; 182(8):1065-72.
  • Shi P, Diez-Freire C, Jun JY, Qi Y, Katovich MJ, Li Q, Sriramula S, Francis J, Sumners C and Raizada MK. Brain microglial cytokines in neurogenic hypertension. Hypertension 2010;56(2):297-303.
  • Boules M, Liang Y, Briody S, Miura T, Fauq I, Oliveros A, Wilson M, Khaniyev S, Williams K, Li Z, Qi Y, Katovich M and Richelson E. NT79: A novel neurotensin analog with selective behavioral effects. Brain Research 2010; 13(1308):35-46.
  • Shenoy V, Grobe JL, Qi Y, Ferreira AJ, Fraga-Silva RA, Collamat G, Bruce E, Katovich MJ. 17beta-Estradiol modulates local cardiac renin-angiotensin system to prevent cardiac remodeling in the DOCA-salt model of hypertension in rats. Peptides. 2009; 30(12):2309-15.
  • Li H, Qi Y, Li C, Braseth LN, Gao Y, Shabashvili AE, Katovich MJ and Sumners C. Angiotensin type 2 receptor-mediated apoptosis of human prostate cancer cells. Molecular Cancer Therapeutics 2009;8(12):3255-65.
  • Hernández Prada JA, Ferreira AJ, Katovich MJ, Shenoy V, Qi Y, Santos RA, Castellano RK, Lampkins AJ, Gubala V, Ostrov DA, Raizada MK. Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. Hypertension. 2008; 51(5):1312-7.
  • Li H, Gao Y, Qi Y, Katovich MJ, Jiang N, Braseth LN, Scheuer DA, Shi P and Sumners C. Macrophage migration inhibitory factor in hypothalamic paraventricular nucleus neurons decreases blood pressure in spontaneously hypertensive rats. The FASEB Journal 2008;22(9):3175-85.
  • Shan K, Qi Y, Qi X, He Y, Li G, Zhang T, Li Y, Wu C, Ren X, Guan Z. Association of genetic polymorphisms of CHRNA4 with sporadic Alzheimer’s disease. Chinese Journal of Gerontology 2008 (28):972-976 (Alzheimer′s病与神经型尼古丁胆碱能受体α4基因多态性关联研究)
  • Shan K, Qi Y, Xu Y, Zhao M, Liu F, Li G, Zhang T, Li Y, Guan Z, Ren X. Association of genetic polymorphisms of CHRNA4,7 with Sporadic Alzheimer’s disease. Journal of Brain and Nervous Diseases 2006,14 (4):256-260 (散发性Alzheimer病与神经型尼古丁胆碱能受体α4α7基因多态性的关联研究)
  • Qi Y, Ren X, Shan K, Xu Y, Zhao M, Liu F, Li G, Zhang T, Li Y, Guan Z. Association between genetic polymorphisms of exon3 of nicotinic acetylcholine receptor α4 subunit and sporadic Alzheimer’s disease. Journal of Clinical Neurology 2006 (3) 452-453 (神经型尼古丁胆碱能受体α4亚单位基因外显子3基因多态性与散发性Alzheimer病的关系)
  • Xie Y, Qi X, Shan K, Qi Y, Li Y, Ma J, Zhao Y, Ren X. Investigation of β-thalassemia in Dong people of Congjiang, Guizhou. Chinese Journal of Endemiology 2005,24 (1):81-82 (贵州从江侗族人群β-地中海贫血调查)
  • Qi Y, Shan K, Xu Y, Zhao M, Liu F, Li G, Zhang T, Li Y, Guan  Z , Ren X. Association of Genetic Polymorphisms of Eexon5 of CHRNA4 with Sporadic Alzheimer Disease. Journal of Guiyang Medical College 2005;30(3):202-206 (中枢型尼古丁胆碱能受体α4外显子5多态性与阿尔茨海默病的关联)
  • Zhao Y, Shan K, Xie Y, He Y, Wu C, Qi X, Li Y, Qi Y, Xiao Y, Mao J, Wu X, Ren X. Sequencing unknown genetic variation of β-thalassemia in Shui Nationality in Sandu,Guizhou. Chinese Journal of Endemiology 2005;24(6):621-624 (贵州三都水族β-地中海贫血未知突变的分析)
  • Zhao Y, Shan K, Yang Q, Li C, Zhou Y, Wu C, Qi Y, Guan Z, Cheng M. Sequencing unknown genetic variation of β-thalassemia in Shui Nationality in Sandu, Guizhou. Chinese Journal of Public Health 2005,21(12):1428-1429 (燃煤型砷中毒患者金属硫蛋白基因表达)
  • Xie Y, Qi X, Qi Y, Li Y, Shan K. Investigation of β-thalassemia in Dong people of Congjiang, Guizhou. Chinese Journal of Public Health 2004,20(7):780-790 (侗族人群β地中海贫血的调查)