Heart Failure


Comparison of Sacubitril/Valsartan Versus Enalapril on Effect on ntpRo-bnp in Patients Stabilized from an Acute Heart Failure Episode

The PIONEER HF research study will compare the effects of an investigational medicine called LCZ696  with those of an approved medicine in reducing the risk of death and rehospitalization in adults who have been hospitalized for acute heart failure.

PIONEER-HF sponsor site

PIONEER-HF on clinicaltrials.gov


A Study of Vericiguat in Participants with Heart Failure with Reduced Ejection Fraction

This is a randomized, placebo-controlled study of the effects of an investigational drug called vericiguat (MK-1242) in participants with heart failure with reduced ejection fraction, to investigate whether vericiguat is superior to placebo in increasing the time to first occurrence of cardiovascular death or heart failure hospitalization.

VICTORIA sponsor site

VICTORIA on clinicaltrials.gov

Please contact our Clinical Trials Office for information: (352) 273-8933 ufcardiovascularct@medicine.ufl.edu