Heart Rhythm Disorders

Acute Myocardial Infarction and High Risk for Ventricular Arrhythmias


  • Vest prevention of Early Sudden death Trial (vest) and PREDiction of ICD Therapies Study (PREDICTS)
  • The purpose of this study is to find out if wearing an external defibrillator (a device that can shock the heart back to a normal rhythm) can prevent death from an abnormal heart beat in people who have had a recent heart attack.
  • Principal Investigator: William Miles

Cardiomyopathy with Implantable Cardiac Defibrillators

Ranolazine ICD Trial (RAID)

  • A Randomized, Double-Blind, Placebo-Controlled Clinical Study To Evaluate The Efficacy And Safety Of Ranolazine Versus Placebo In Patients With Implantable Cardiac Defibrillators
  • The purpose of this research study is to see how effective the drug Ranolazine is in reducing the risk of fast cardiac arrhythmias and death in people with implantable cardioverter defibrillators (ICDs). Ranolazine was approved by FDA in 2006 for angina, and in 2009 for anti-anginal therapy. It has not been approved for the prevention and treatment of cardiac arrhythmias. This drug will be used with standard medications used to treat the heart.
  • Principal Investigator: William Miles

Please contact our Clinical Trials Office for information: (352) 273-8933