Chest Pain/Angina

Non-obstructive Angina


  • Women’s Ischemia Syndrome Evaluation (WISE) Coronary Vascular Dysfunction
    The purpose of this research study is to better understand chest pain in women that are suspected to have ischemia or insufficient blood flow, by comparing noninvasive test results to invasive test results.
  • Principal Investigator: Carl Pepine

Microvascular Dysfunction


  • Treatment of Ranolazine in Microvascular Coronary Dysfunction (MCD): Impact on Angina and Myocardial Ischemia (R-WISE)
  • The purpose of this study is to test the use of the drug Ranolazine in people who suffer with angina from microvascular coronary dysfunction (MCD). Angina is chest discomfort due to reduced blood supply to the heart and MCD is caused by abnormalities in the small blood vessels of the heart. Ranolazine is an FDA approved drug.
  • Principal Investigator: Carl Pepine

Please contact our Clinical Trials Office for information: (352) 273-8933