R. David Anderson

R. David Anderson, MD, MS, FACC, FSCAI

Clinical Professor

Department: MD-CARDIOLOGY
Business Phone: (352) 265-0820

About R. David Anderson

My name is R. David Anderson, MD, MS, FACC, FSCAI, and I am a professor of medicine in the University of Florida Division of Cardiovascular Medicine and the director of interventional cardiology and cardiac catheterization. Most call me Dave, but some prefer to call me R. David. Prior to joining UF Health, I worked in the Sarasota Memorial Hospital Division of Cardiology in the 2000s.

I received my medical degree from Johns Hopkins University in 1990. Then, I completed an internship followed by residency at the University of Maryland Hospital. During my residency, I received the title of chief resident in the department of medicine. Afterward, I completed a fellowship at Duke University Medical Center.

I was drawn to medicine by the idea of trying to help people in any way possible. If you listen, everyone has a story, and I have benefitted the most from getting to know my patients’ stories. I want my patients to know that I will listen, always have their best interest in mind and would never offer them a treatment or procedure without a reasonable expectation of it helping them. I have had a career that has been satisfying in so many ways. I feel lucky to have helped build a successful interventional cardiology program at UF Health and am grateful for my partners and their superb care of patients. I am perhaps most proud to have been involved in the successful training of nearly 50 interventional cardiologists over the years. I have been lucky to receive teaching accolades over the years, but Master Clinician and the 2022 Exemplary Teacher awards are most appreciated.

I have written numerous abstracts on coronary vascular dysfunction and other heart diseases, and I have two patents — the auto perfusion dilatation catheter and a new rapid exchange/auto perfusion angioplasty balloon catheter. My research has focused on the use of stem cells to treat and improve heart disease, and I have been very involved in the study of coronary microvascular disease. Recently, my research has expanded to include structural heart disease, particularly the study of transcatheter therapy for valvular heart disease.

Outside of work, I try to spend as much of my free time as possible with my kids, who are mostly grown. They are all successful, and that is extremely gratifying. I also spend a lot of time in triathlons and have completed several Ironman distance events, even recently placing second at Ironman Florida.

Accomplishments

Master Clinician Award
2013 · University of Florida
Excellence in teaching Medical Students
2007-2009 · University of Florida
Chief Resident Physician in Internal Medicine
1994 · University of Maryland

Teaching Profile

Courses Taught
2020-2021
BMS6633 The Cv System
2018
MDC6001 Intro Clin Practice

Board Certifications

  • Cardiovascular Disease
    American Board of Internal Medicine
  • Interventional Cardiology
    American Board of Internal Medicine

Clinical Profile

Specialties
  • Cardiology
  • General Internal Medicine
  • Interventional Cardiology
Areas of Interest
  • Acute coronary syndrome
  • Cardiac catheterization
  • Coronary heart disease
  • High blood pressure – adults
  • Transcatheter aortic valve replacement (TAVR)
  • Valvular Disease

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-3490-3286

Areas of Interest
  • Coronary Vascular Dysfunction

Publications

2024
CYP2C19 Genotype Is Associated With Adverse Cardiovascular Outcomes in Black Patients Treated With Clopidogrel Undergoing Percutaneous Coronary Intervention
Journal of the American Heart Association. 13(12) [DOI] 10.1161/jaha.123.033791.
2023
Aspirin Dosing for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Patients Treated With P2Y12 Inhibitors
Journal of the American Heart Association. 12(20) [DOI] 10.1161/jaha.123.030385.
2023
EXACT Trial: Results of the Phase 1 Dose-Escalation Study
Circulation: Cardiovascular Interventions. 16(8) [DOI] 10.1161/circinterventions.123.012997.
2021
Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease
New England Journal of Medicine. 1981-1990 [DOI] 10.1056/NEJMoa2102137Copyright<(c)>2021Massachusetts.
2020
Angina Hospitalization Rates in Women With Signs and Symptoms of Ischemia But no Obstructive Coronary Artery Disease: A Report from the WISE (Women’s Ischemia Syndrome Evaluation) Study.
Journal of the American Heart Association. 9(4) [DOI] 10.1161/JAHA.119.013168. [PMID] 32063125.
2020
Cardiovascular Considerations for the Internist and Hospitalist in the COVID-19 Era
The American Journal of Medicine. 133(11):1254-1261 [DOI] 10.1016/j.amjmed.2020.06.005. [PMID] 32653420.
2020
Design, methodology and baseline characteristics of the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD).
American heart journal. 220:224-236 [DOI] 10.1016/j.ahj.2019.11.017. [PMID] 31884245.
2020
Does ischemia also change as we age?
Jacc-Cardiovascular Interventions. 13:30-32
2020
Editorial: The use of Fascia iliaca Block with Minimal Conscious Sedation in Transcatheter Aortic Valve Replacement: Advances in TAVR Anesthesia.
Cardiovascular revascularization medicine : including molecular interventions. 21(5):602-603 [DOI] 10.1016/j.carrev.2020.03.017. [PMID] 32201210.
2020
Incidence, Clinical Presentation, and Causes of 30-Day Readmission Following Hospitalization With Spontaneous Coronary Artery Dissection.
JACC. Cardiovascular interventions. 13(8):921-932 [DOI] 10.1016/j.jcin.2019.12.033. [PMID] 32327089.
2020
Myocardial infarction and persistent angina with no obstructive coronary artery disease
. 2:9-14
2020
Percutaneous inferior vena cava valve implantation may improve tricuspid valve regurgitation and cardiac output: Lessons learned
Innovations (Philadelphia, Pa. Online).
2020
Resting coronary velocity and myocardial performance in women with impaired coronary flow reserve: Results from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) study.
International journal of cardiology. 309:19-22 [DOI] 10.1016/j.ijcard.2020.01.053. [PMID] 32037132.
2019
Drug-Eluting Balloons Versus Everolimus-Eluting Stents for In-Stent Restenosis: A Meta-Analysis of Randomized Trials
Cardiovascular revascularization medicine : including molecular interventions. 20(7):612-618 [DOI] 10.1016/j.carrev.2018.08.010.
2019
Is it time to eliminate balloon valvuloplasty before transcatheter aortic valve replacement?
International journal of cardiology. 296:53-54 [DOI] 10.1016/j.ijcard.2019.08.041. [PMID] 31477315.
2019
Left ventricular concentric remodelling and functional impairment in women with ischaemia with no obstructive coronary artery disease and intermediate coronary flow reserve: a report from the WISE-CVD study.
European heart journal. Cardiovascular Imaging. 20(8):875-882 [DOI] 10.1093/ehjci/jez044. [PMID] 30904924.
2019
Outcomes of direct transcatheter aortic valve replacement without balloon aortic valvuloplasty using a new generation valve
Cardiovascular revascularization medicine : including molecular interventions.
2019
Prevalence of Coronary Endothelial and Microvascular Dysfunction in Women with Symptoms of Ischemia and No Obstructive Coronary Artery Disease Is Confirmed by a New Cohort: The NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation–Coronary Vascular Dysfunction (WISE-CVD)
Journal of Interventional Cardiology. 2019:1-8 [DOI] 10.1155/2019/7169275. [PMID] 31772544.
2019
The functional assessment of patients with non-obstructive coronary artery disease: Expert review from an international microcirculation working group
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 14(16):1694-1702
2018
Current status of coronary atherectomy
Cardiovascular Innovations and Applications. 3(2):203-214
2018
Early and midterm outcomes of transcatheter aortic valve replacement in patients with bicuspid aortic valves.
Journal of cardiac surgery. 33(9):489-496 [DOI] 10.1111/jocs.13775. [PMID] 30058259.
2018
Efficiency Improvements in the Catheterization Laboratory: It’s All About the Team.
JACC. Cardiovascular interventions. 11(4):339-341 [DOI] 10.1016/j.jcin.2017.10.031. [PMID] 29397362.
2018
Intracoronary Bolus Injection Versus Intravenous Infusion of Adenosine for Assessment of Coronary Flow Velocity Reserve in Women With Signs and Symptoms of Myocardial Ischemia and No Obstructive Coronary Artery Disease.
JACC. Cardiovascular interventions. 11(20):2125-2127 [DOI] 10.1016/j.jcin.2018.07.052. [PMID] 30336817.
2018
Maladaptive left ventricular remodeling in women: An analysis from the Women’s Ischemia Syndrome Evaluation–Coronary Vascular Dysfunction study
International Journal of Cardiology. 268:230-235 [DOI] 10.1016/j.ijcard.2018.03.139. [PMID] 30041793.
2018
Meta-Analysis of Aspirin Versus Dual Antiplatelet Therapy Following Coronary Artery Bypass Grafting
American Journal of Cardiology. 121(1):32-40 [DOI] 10.1016/j.amjcard.2017.09.022.
2018
Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.
JACC. Cardiovascular interventions. 11(2):181-191 [DOI] 10.1016/j.jcin.2017.07.022. [PMID] 29102571.
2018
Prevalence, Causes, and Predictors of 30-Day Readmissions Following Hospitalization With Acute Myocardial Infarction Complicated By Cardiogenic Shock: Findings From the 2013-2014 National Readmissions Database.
Journal of the American Heart Association. 7(6) [DOI] 10.1161/JAHA.117.008235. [PMID] 29572325.
2018
Safety and efficacy of second-generation drug-eluting stents compared with bare-metal stents: An updated meta-analysis and regression of 9 randomized clinical trials.
Clinical cardiology. 41(1):151-158 [DOI] 10.1002/clc.22855. [PMID] 29369375.
2018
Statin Use in Men and New Onset of Erectile Dysfunction: A Systematic Review and Meta-Analysis.
The American journal of medicine. 131(4):387-394 [DOI] 10.1016/j.amjmed.2017.10.043. [PMID] 29146233.
2018
Temporal Trends in Inpatient Use of Intravascular Imaging Among Patients Undergoing Percutaneous Coronary Intervention in the United States.
JACC. Cardiovascular interventions. 11(9):913-915 [DOI] 10.1016/j.jcin.2018.01.254. [PMID] 29747923.
2018
Transcatheter Aortic Valve Replacement Efficiency and Safety Improvements With Progressive Experience and Improved Technology
Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. 13(2):120-124 [DOI] 10.1097/IMI.0000000000000480.
2018
Trends of Incidence, Clinical Presentation, and In-Hospital Mortality Among Women With Acute Myocardial Infarction With or Without Spontaneous Coronary Artery Dissection a Population-Based Analysis
Jacc-Cardiovascular Interventions. 11(1):80-90 [DOI] 10.1016/j.jcin.2017.08.016.
2017
Acetylcholine versus cold pressor testing for evaluation of coronary endothelial function.
PloS one. 12(2) [DOI] 10.1371/journal.pone.0172538. [PMID] 28207868.
2017
Cardiac Pneumonia: Acute Mitral Regurgitation Causing Lobar Infiltrate.
The American journal of medicine. 130(4):e147-e148 [DOI] 10.1016/j.amjmed.2016.10.032. [PMID] 28325226.
2017
Cold Pressor Stress Cardiac Magnetic Resonance Myocardial Flow Reserve Is Not Useful for Detection of Coronary Endothelial Dysfunction in Women with Signs and Symptoms of Ischemia and No Obstructive CAD.
PloS one. 12(1) [DOI] 10.1371/journal.pone.0169818. [PMID] 28081214.
2017
Comparison of Periprocedural and Mid-Term Stroke Rates and Outcomes Between Surgical Aortic Valve Replacement and Transcatheter Aortic Valve Replacement Patients
Journal of Cardiovascular Surgery. 58(4):591-597 [DOI] 10.23736/S0021-9509.16.09390-3.
2017
Daily Activity Measured With Wearable Technology as a Novel Measurement of Treatment Effect in Patients With Coronary Microvascular Dysfunction: Substudy of a Randomized Controlled Crossover Trial
JMIR Research Protocols. 6(12) [DOI] 10.2196/resprot.8057. [PMID] 29263019.
2017
Early Invasive Strategy and In-Hospital Survival Among Diabetics With Non-ST-Elevation Acute Coronary Syndromes: A Contemporary National Insight.
Journal of the American Heart Association. 6(3) [DOI] 10.1161/JAHA.116.005369. [PMID] 28315826.
2017
Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).
Circulation. 135(15):1417-1428 [DOI] 10.1161/CIRCULATIONAHA.116.025707. [PMID] 28209728.
2017
Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Disease: a Meta-Analysis and Regression of Randomized Trials
Catheterization and cardiovascular interventions.. 90(4):541-552 [DOI] 10.1002/ccd.26970.
2017
Safety and Efficacy of Dual Versus Triple Antithrombotic Therapy in Patients Undergoing Percutaneous Coronary Intervention
The American journal of medicine. 130(11):1280-1289 [DOI] 10.1016/j.amjmed.2017.03.057.
2017
Staged Versus Index Procedure Complete Revascularization in St-Elevation Myocardial Infarction: a Meta-Analysis
Journal of Interventional Cardiology. 30(5):397-404 [DOI] 10.1111/joic.12414.
2017
The Athena Trials: Autologous Adipose-Derived Regenerative Cells for Refractory Chronic Myocardial Ischemia With Left Ventricular Dysfunction
Catheterization and cardiovascular interventions.. 89(2):169-177 [DOI] 10.1002/ccd.26601.
2017
When ablation is not the answer: Acute left main thrombosis causing incessant ventricular tachycardia following left ventricular assist device implant
Cureus. 9(10)
2016
A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve.
European heart journal. 37(19):1504-13 [DOI] 10.1093/eurheartj/ehv647. [PMID] 26614823.
2016
Acute Kidney Injury After Transcatheter Aortic Valve Replacement
Journal of Cardiac Surgery. 31(7):416-422 [DOI] 10.1111/jocs.12768.
2016
Association between High Endocardial Unipolar Voltage and Improved Left Ventricular Function in Patients with Ischemic Cardiomyopathy.
Texas Heart Institute journal. 43(4):291-6 [DOI] 10.14503/THIJ-15-5341. [PMID] 27547135.
2016
Circulating progenitor cells and coronary microvascular dysfunction: Results from the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation – Coronary Vascular Dysfunction Study (WISE-CVD).
Atherosclerosis. 253:111-117 [DOI] 10.1016/j.atherosclerosis.2016.08.026. [PMID] 27596135.
2016
Coronary artery chronic total occlusion
Cardiovascular Innovations and Applications. 1(3):325-335
2016
Does RIDDLE-NSTEMI Provide an Answer to the Timing of ACS Therapy?
JACC. Cardiovascular interventions. 9(6):550-2 [DOI] 10.1016/j.jcin.2016.01.020. [PMID] 27013154.
2016
Ixmyelocel-T for Patients With Ischaemic Heart Failure: a Prospective Randomised Double-Blind Trial
Lancet. 387(10036):2412-2421 [DOI] 10.1016/S0140-6736(16)30137-4.
2016
Ranolazine in patients with incomplete revascularisation after percutaneous coronary intervention (RIVER-PCI): a multicentre, randomised, double-blind, placebo-controlled trial.
Lancet (London, England). 387(10014):136-45 [DOI] 10.1016/S0140-6736(15)00459-6. [PMID] 26474810.
2016
Renal denervation: Past, present, and future
Cardiovascular Innovations and Applications. 1(3):253-263
2015
Acute kidney injury after transcatheter aortic valve replacement
American Journal of Nephrology. 41(4-5):370-371
2015
Are We There Yet?: Should All Comatose Cardiac Arrest Survivors Go to the Cath Lab?
JACC. Cardiovascular interventions. 8(8):1041-1043 [DOI] 10.1016/j.jcin.2015.05.004. [PMID] 26205443.
2015
Changes in ventricular remodelling and clinical status during the year following a single administration of stromal cell-derived factor-1 non-viral gene therapy in chronic ischaemic heart failure patients: the STOP-HF randomized Phase II trial.
European heart journal. 36(33):2228-38 [DOI] 10.1093/eurheartj/ehv254. [PMID] 26056125.
2015
Cognitive-Motivational Influences On Health Behavior Change in Chronic Pain
Journal of Pain. 16(4, 1)
2015
Long-term use of ticagrelor in patients with prior myocardial infarction.
The New England journal of medicine. 372(19):1791-800 [DOI] 10.1056/NEJMoa1500857. [PMID] 25773268.
2015
Relationships between components of metabolic syndrome and coronary intravascular ultrasound atherosclerosis measures in women without obstructive coronary artery disease: the NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation Study.
Cardiovascular endocrinology. 4(2):45-52 [PMID] 26665010.
2014
Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the cardiovascular cell therapy research network.
Circulation research. 114(10):1564-8 [DOI] 10.1161/CIRCRESAHA.114.303720. [PMID] 24812350.
2014
Clinical pharmacogenetics implementation: approaches, successes, and challenges.
American journal of medical genetics. Part C, Seminars in medical genetics. 166C(1):56-67 [DOI] 10.1002/ajmg.c.31390. [PMID] 24616371.
2014
Comparison of low and high dose intracoronary adenosine and acetylcholine in women undergoing coronary reactivity testing: results from the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE).
International journal of cardiology. 172(1):e114-5 [DOI] 10.1016/j.ijcard.2013.12.120. [PMID] 24461979.
2014
Drug-eluting stents may not reduce target lesion revascularization in cardiac allograft vasculopathy.
Journal of interventional cardiology. 27(1):80-5 [DOI] 10.1111/joic.12088. [PMID] 24383617.
2014
Rationale and design for PACE: patients with intermittent claudication injected with ALDH bright cells.
American heart journal. 168(5):667-73 [DOI] 10.1016/j.ahj.2014.07.021. [PMID] 25440794.
2014
Sdf-1 Plasmid Attenuates Adverse Remodeling in Ischemic Heart Failure Patients in a Randomized Phase II Trial
. 20(8, S):S9-S10
2014
TIMI frame count and adverse events in women with no obstructive coronary disease: a pilot study from the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE).
PloS one. 9(5) [DOI] 10.1371/journal.pone.0096630. [PMID] 24800739.
2013
Adverse outcomes among women presenting with signs and symptoms of ischemia and no obstructive coronary artery disease: findings from the National Heart, Lung, and Blood Institute-sponsored Women’s Ischemia Syndrome Evaluation (WISE) angiographic core laboratory.
American heart journal. 166(1):134-41 [DOI] 10.1016/j.ahj.2013.04.002. [PMID] 23816032.
2013
Coronary angiography: is it time to reassess?
Circulation. 127(17):1760-2 [DOI] 10.1161/CIRCULATIONAHA.113.002566. [PMID] 23630085.
2013
Electromechanical Assessment of Myocardial Function (Noga) Is Associated With Exercise Improvement in Patients Treated With Autologous Stem Cell Therapy for Refractory Angina
Journal of the American College of Cardiology. 61
2013
Electromechanical Assessment of Myocardial Function Is Associated With Improvement in Ejection Fraction in Patients Treated With Autologous Stem Cell Therapy for Ischemic Cardiomyopathy
Circulation. 128(22, S)
2013
Increased Circulating Progenitor Cells in Women With Microvascular Coronary Dysfunction: Results From the Nhlbi-Sponsored Women’s Ischemia Syndrome Evaluation – Coronary Vascular Dysfunction Study (Wise-Cvd)
Circulation. 128(22, S)
2013
Multimodality direct coronary imaging with combined near-infrared spectroscopy and intravascular ultrasound: initial US experience.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 81(3):551-7 [DOI] 10.1002/ccd.23358. [PMID] 22110009.
2012
Differential Effects of Cold Pressor and Acetylcholine During Endothelial Function Assessment in Women With No Obstructive Coronary Artery Disease: the Nhlbi-Sponsored Women’S Ischemia Syndrome Evaluation (Wise) Study
Journal of the American College of Cardiology. 59
2012
Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial.
JAMA. 308(22):2380-9 [PMID] 23129008.
2012
Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells On Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure the Focus-Cctrn Trial
Jama-Journal of the American Medical Association. 307:1717-1726
2012
Relationships Between Components of Metabolic Syndrome and Coronary Intravascular Ultrasound (Ivus) Atherosclerosis Measures in Women Without Obstructive Coronary Artery Disease: the Nhlbi-Sponsored Women’S Ischemia Syndrome Evaluation (Wise) Study
Journal of the American College of Cardiology. 59(13, S)
2012
Safety of coronary reactivity testing in women with no obstructive coronary artery disease: results from the NHLBI-sponsored WISE (Women’s Ischemia Syndrome Evaluation) study.
JACC. Cardiovascular interventions. 5(6):646-53 [DOI] 10.1016/j.jcin.2012.01.023. [PMID] 22721660.
2012
Simple Main Branch Only Stenting Is Preferable To Complex Bifurcation Intervention Regardless of the Side Branch Strategy: a Meta-Analysis of Randomized Clinical Trials
Journal of the American College of Cardiology. 59
2012
Strategies for multivessel revascularization in patients with diabetes.
The New England journal of medicine. 367(25):2375-84 [DOI] 10.1056/NEJMoa1211585. [PMID] 23121323.
2011
A randomized two-by-two comparison of high-dose bolus tirofiban versus abciximab and unfractionated heparin versus bivalirudin during percutaneous coronary revascularization and stent placement: the tirofiban evaluation of novel dosing versus abciximab with clopidogrel and inhibition of thrombin (TENACITY) study trial.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 77(7):1001-9 [DOI] 10.1002/ccd.22876. [PMID] 21598351.
2011
Could Retinal Imaging Provide a Simple, Inexpensive, Noninvasive Index for Coronary Microvascular Function in Women With Chest Pain and Nonobstructive Coronary Artery Disease? An Ancillary Pilot Study From the Nhlbi-Sponsored Women’s Ischemia Syndrome Evaluation (Wise-Aric)
Journal of the American College of Cardiology. 57
2011
Does Angiotensin Plus Aldosterone Inhibition Improve Coronary Endothelial Function? An Ancillary Study From the Nhlbi-Sponsored Women’s Ischemia Syndrome Evaluation (Wise)
Journal of the American College of Cardiology. 57
2011
Efficacy and safety of glycoprotein IIb/IIIa inhibitors during elective coronary revascularization: a meta-analysis of randomized trials performed in the era of stents and thienopyridines.
Journal of the American College of Cardiology. 57(10):1190-9 [DOI] 10.1016/j.jacc.2010.10.030. [PMID] 21371635.
2011
In women with symptoms of cardiac ischemia, nonobstructive coronary arteries, and microvascular dysfunction, angiotensin-converting enzyme inhibition is associated with improved microvascular function: A double-blind randomized study from the National Heart, Lung and Blood Institute Women’s Ischemia Syndrome Evaluation (WISE).
American heart journal. 162(4):678-84 [DOI] 10.1016/j.ahj.2011.07.011. [PMID] 21982660.
2011
Relationship Between Coronary Micro- and Macrovascular Measures in Women With Chest Pain Without Significant Coronary Artery Disease: An Ancillary Substudy From the Nhbli-Sponsored Women’s Ischemia Syndrome Evaluation (Wise)
Journal of the American College of Cardiology. 57
2010
An intravascular ultrasound analysis in women experiencing chest pain in the absence of obstructive coronary artery disease: a substudy from the National Heart, Lung and Blood Institute-Sponsored Women’s Ischemia Syndrome Evaluation (WISE).
Journal of interventional cardiology. 23(6):511-9 [DOI] 10.1111/j.1540-8183.2010.00598.x. [PMID] 21029178.
2010
Coronary microvascular reactivity to adenosine predicts adverse outcome in women evaluated for suspected ischemia results from the National Heart, Lung and Blood Institute WISE (Women’s Ischemia Syndrome Evaluation) study.
Journal of the American College of Cardiology. 55(25):2825-32 [DOI] 10.1016/j.jacc.2010.01.054. [PMID] 20579539.
2010
Left internal mammary artery graft decompression by covered stent treatment of an adjacent saphenous vein graft pseudoaneurysm.
JACC. Cardiovascular interventions. 3(6):688-90 [DOI] 10.1016/j.jcin.2009.12.017. [PMID] 20630464.
2010
Outcomes Among hypertensive patients with concomitant peripheral and coronary artery disease: findings from the INternational VErapamil-SR/Trandolapril STudy.
Hypertension (Dallas, Tex. : 1979). 55(1):48-53 [DOI] 10.1161/HYPERTENSIONAHA.109.142240. [PMID] 19996066.
2009
Acute Evaluation of the Mynx (Tm) Vascular Closure Device During Arterial Re-Puncture in An Ovine Model
Journal of Invasive Cardiology. 21:283-285
2008
Blood pressure targets after high-risk myocardial infarction: is it time to update the guidelines?
Hypertension (Dallas, Tex. : 1979). 51(1):26-7 [PMID] 18039982.
2008
Pulse pressure and adverse outcomes in women: a report from the Women’s Ischemia Syndrome Evaluation (WISE).
American journal of hypertension. 21(11):1224-30 [DOI] 10.1038/ajh.2008.268. [PMID] 18802432.
2008
Response To the J-Point Revisited
Hypertension. 51(5) [DOI] 10.1161/HYPERTENSIONAHA.108.109983.
2008
The optimal treatment of carotid atherosclerosis: a 2008 update and literature review.
Postgraduate medicine. 120(3):103-12 [DOI] 10.3810/pgm.2008.09.1911. [PMID] 18824829.
2008
Treatment of a ruptured saphenous vein graft pseudoaneurysm using a vascular plug.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 71(5):587-9 [DOI] 10.1002/ccd.21456. [PMID] 18360846.
2007
Gender differences in the treatment for acute myocardial infarction: bias or biology?
Circulation. 115(7):823-6 [PMID] 17309930.
2007
Results from a phase II multicenter, double-blind placebo-controlled study of Del-1 (VLTS-589) for intermittent claudication in subjects with peripheral arterial disease.
American heart journal. 153(5):874-80 [PMID] 17452167.
2002
Predicting outcome after thrombolysis in acute myocardial infarction according to ST-segment resolution at 90 minutes: a substudy of the GUSTO-III trial. Global Use of Strategies To Open occluded coronary arteries.
American heart journal. 144(1):81-8 [PMID] 12094192.
2002
Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial.
Lancet (London, England). 359(9323):2053-8 [PMID] 12086757.
2001
Design of the therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (TRAFFIC) trial.
The American journal of cardiology. 88(2):192-5, A6 [PMID] 11448424.
2001
Does the presence of thrombus seen on a coronary angiogram affect the outcome after percutaneous coronary angioplasty? An Angiographic Trials Pool data experience.
Journal of the American College of Cardiology. 38(3):624-30 [PMID] 11527607.
2000
Lack of progress in cardiogenic shock: lessons from the GUSTO trials.
European heart journal. 21(23):1928-36 [PMID] 11071798.
1998
Prognostic value of congestive heart failure history in patients undergoing percutaneous coronary interventions.
Journal of the American College of Cardiology. 32(4):936-41 [PMID] 9768714.
1997
A comparison of reteplase with alteplase for acute myocardial infarction.
The New England journal of medicine. 337(16):1118-23 [PMID] 9340503.
1997
Coronary artery angioplasty with a helical autoperfusion balloon catheter.
Catheterization and cardiovascular diagnosis. 40(2):179-85 [PMID] 9047063.
1997
New concept in coronary angioplasty: dilatation with a helical balloon that allows simultaneous autoperfusion.
Catheterization and cardiovascular diagnosis. 40(1):109-16 [PMID] 8993827.
1997
Relationship between diabetes mellitus and long-term survival after coronary bypass and angioplasty.
Circulation. 96(8):2551-6 [PMID] 9355893.
1997
Use of intraaortic balloon counterpulsation in patients presenting with cardiogenic shock: observations from the GUSTO-I Study. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries.
Journal of the American College of Cardiology. 30(3):708-15 [PMID] 9283530.
1996
Successful identification and management of high-risk patients with acute myocardial infarction
Journal of thrombosis and thrombolysis (Dordrecht. Online). 3(3):271-278
1996
The effect of intra-aortic balloon counterpulsation on coronary blood flow velocity distal to coronary artery stenoses.
Cardiology. 87(4):306-12 [PMID] 8793165.
1994
A canine model of acute coronary artery thrombosis for the evaluation of reperfusion strategies.
Cardiology. 84(1):1-8 [PMID] 8149384.
1994
Accelerated intravenous dosing of recombinant tissue-type plasminogen activator causes rapid but unstable reperfusion in a canine model of acute myocardial infarction.
Coronary artery disease. 5(11):929-36 [PMID] 7719525.
1994
Arterial diastolic pressure augmentation by intra-aortic balloon counterpulsation enhances the onset of coronary artery reperfusion by thrombolytic therapy.
Circulation. 89(1):361-5 [PMID] 8281671.
Daily Activity Measured With Wearable Technology as a Novel Measurement of Treatment Effect in Patients With Coronary Microvascular Dysfunction: Substudy of a Randomized Controlled Crossover Trial (Preprint)
. [DOI] 10.2196/preprints.8057.

Grants

Mar 2024 ACTIVE
Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI DTU Trial
Role: Principal Investigator
Funding: ABIOMED
Jul 2023 ACTIVE
Phase I/II Clinical Trial of Human Allogeneic Cultureexpanded Bone marrow-derived Mesenchymal Stem Cells (hMSCs) in Patients with Ischemic Heart Failure with reduced ejection fraction (HFrEF) (CardiALLO NK1R+ MSC Trial)8
Role: Principal Investigator
Funding: BIOCARDIA
Jul 2022 ACTIVE
Impella-Supported PCI in High-Risk Patients with Complex Coronary Artery Disease and Reduced Left Ventricular Function: The PROTECT IV Trial
Role: Principal Investigator
Funding: ABIOMED
Jul 2021 ACTIVE
SMall Annuli Randomized To Evolut or SAPIEN Trial
Role: Principal Investigator
Funding: MEDTRONIC INC
Feb 2021 ACTIVE
A Double-Blind, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of CLBS16 Delivery in Subjects with Coronary Microvascular Dysfunction and Without Obstructive Coronary Artery Disease
Role: Principal Investigator
Funding: CALADRIUS BIOSCIENCES
Dec 2020 ACTIVE
Randomized Controlled Pivotal Trial of Autologous Bone Marrow Mononuclear Cells Using the CardiAMP Cell Therapy system in Patients with refractory chronic myocardial ischemia
Role: Principal Investigator
Funding: BIOCARDIA
Sep 2020 – Aug 2024
Effect of Intensive Medical Treatment on Quantified Coronary Artery Plaque Components with Serial Coronary CTA in Women with Non-Obstructive CAD
Role: Co-Investigator
Funding: CEDARS SINAI MEDICAL CTR via NATL INST OF HLTH NHLBI
Jan 2020 ACTIVE
A Phase 1/2 Trial of Direct Administration of AdVEGF-All6A+, a Replication Deficient Adenovirus Vector Expressing a cDNA/Genomic Hybrid of Human Vascular Endothelial Growth Factor, to the Ischemic Myocardium of Subjects with Angina Pectoris Secondary to Coronary Artery Disease that is Refractory to Drug Therapy and Unsuitable for Revascularization
Role: Principal Investigator
Funding: XYLOCOR THERAPEUTICS
Nov 2019 ACTIVE
A Pivotal, Multicenter, Blinded, Sham Procedure-Controlled Trial of Renal Denervation by the Peregrine System Kit, in Subjects with Hypertension
Role: Principal Investigator
Funding: ABLATIVE SOLUTIONS
May 2019 ACTIVE
Womens Ischemia Syndrome Evaluation (WISE) Mechanisms of Coronary Microvascular Dysfunction Leading to Pre-Heart Failure with Preserved Ejection Fraction (HFpEF)
Role: Co-Investigator
Funding: CEDARS SINAI MEDICAL CTR via NATL INST OF HLTH NHLBI
Sep 2017 ACTIVE
Women's Ischemia Trial to Reduce Events in Non-Obstructive CAD (WARRIOR)
Role: Project Manager
Funding: US ARMY MED RES ACQUISITION
Mar 2017 – Sep 2023
A Phase I, Open-label Study of the Effects of Percutaneous Administration of an Extracellular Matrix Hydrogel, VentriGel, Following Myocardial Infarction
Role: Principal Investigator
Funding: VENTRIX INC
Sep 2016 – Jun 2021
Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE)
Role: Principal Investigator
Funding: DUKE UNIVERSITY via PATIENT-CENTERED OUTCOMES RES INST
Sep 2016 – May 2024
Randomized Controlled Pivotal Trial of Autologous Bone Marrow Mononuclear Cells Using the CardiAMP System in Patients with Post Myocardial Infarction Heart Failure (CardiAMP Heart Failure Trial)
Role: Principal Investigator
Funding: BIOCARDIA
Jun 2016 – Apr 2017
A Randomized Evaluation oF the TriGuard HDH Embolic Deflection Device to Reduce the Impact of Cerebral Embolic LEsions after TransCatheter Aortic Valve ImplanTation
Role: Principal Investigator
Funding: *KEYSTONE HEART
May 2016 – Oct 2023
ALLSTAR (ALLOGENEIC HEART STEM CELLS TO ACHIEVE MYOCARDIAL REGENERATION)
Role: Principal Investigator
Funding: CAPRICOR, INC.
May 2016 – Nov 2022
PHASE 2 PROSPECTIVE RANDOMIZED DOUBLE BLIND SHAM CONTROLLED PARALLEL GROUP MULTI CENTER TRIAL OF AMI MULTISTEM IN ……
Role: Principal Investigator
Funding: ABT HOLDING COMPANY
May 2016 – Oct 2022
AFFORDABILITY AND REAL-WORLD ANTIPLATELET TREATMENT EFFECTIVENESS AFTER MYOCARDIAL INFARCTION STUDY
Role: Principal Investigator
Funding: DUKE UNIVERSITY via ASTRAZENECA
May 2016 – Jan 2018
RENAL DENERVATION IN PATIENTS WITH UNCONTROLLED HYPERTINSION- SYMPLICITY HTN-3
Role: Principal Investigator
Funding: MEDTRONIC VASCULAR
Oct 2015 – Oct 2018
Affordability and Real-world Antiplatelet Treatment Effectiveness After Myocardial Infarction Study
Role: Principal Investigator
Funding: DUKE UNIVERSITY via ASTRAZENECA
Sep 2015 – Jul 2023
SALUS The Direct Flow Medical Transcatheter Aortic Valve Replacement System Pivotal Trial The Safety and Effectiveness of the Direct Flow Medical Transcatheter Aortic Valve System
Role: Principal Investigator
Funding: DIRECT FLOW MEDICAL INC
May 2014 – May 2017
A Registry to Assess the Ongoing Safety for Subjects that have been Randomized and Completed a Juventas Sponsored Heart Failure Protocol under IND # 14203
Role: Principal Investigator
Funding: JUVENTAS THERAPEUTICS
Feb 2014 – Oct 2022
A Multicenter, Randomized,Double-blind,Placebo-controlled, Parallel Group Study to Evaluate the Efficacy, Safety, and Tolerability of Transendocardial Injection of Ixmyelocel-T in Subjects with Heart Failure due to Ischemic Dilated Cardiomyopathy
Role: Principal Investigator
Funding: AASTROM BIOSCIENCES
Nov 2013 – Nov 2016
A Phase I/II Study to Evaluate the Safety and Efficacy of JVS-100 Administered by Retrograde Delivery to Cohorts of Adults with Ischemic Heart Failure
Role: Principal Investigator
Funding: JUVENTAS THERAPEUTICS
Oct 2013 ACTIVE
ANDERSON PAYROLL OPERATING ACCOUNT
Role: Principal Investigator
Funding: 214 OPERATING ACCOUNT
May 2012 – Apr 2017
Renal Denervation in Patients with Uncontrolled Hypertension SYMPLICITY HTN-3
Role: Principal Investigator
Funding: MEDTRONIC VASCULAR
Mar 2012 – Aug 2020
UFRCC for Cardiovascular Cell Therapy Research Network
Role: Co-Investigator
Funding: NATL INST OF HLTH NHLBI
Jan 2011 – Jan 2017
A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multinational Trial, to Assess the Prevention of Thrombotic Events with Ticagrelor Compared to Placebo on a Background of Acetyl Salicylic Acid (ASA) Therapy in Patients with History of Myoc
Role: Principal Investigator
Funding: BRIGHAM AND WOMENS HOSPITAL via ASTRAZENECA
Sep 2008 – Mar 2016
Patient Related Outcomes with Endeavor Versus Cypher Stenting Trial
Role: Principal Investigator
Funding: MEDTRONIC INC

Education

Fellowship
1994-1998 · Duke University Medical Center
Residency
1991-1994 · University of Maryland Hospital
Internship
1990-1991 · University of Maryland Hospital
Medical Degree
1986-1990 · Johns Hopkins University
Master's Degree
1983-1986 · University of Pennsylvania
Bachelor's Degree
1975-1979 · Stevens Institute of Technology

Contact Details

Phones:
Business:
(352) 265-0820
Administrative Spec III:
Addresses:
Business Mailing:
PO Box 100288
1329 SW 16TH ST
GAINESVILLE FL 32610
Business Street:
1600 SW ARCHER RD
GAINESVILLE FL 32610