Keith March

Keith March

VA Faculty

Department: MD-CARDIOLOGY
Business Phone: (352) 294-8620

Publications

2021
Adipose stem cell secretome markedly improves rodent heart and human induced pluripotent stem cell-derived cardiomyocyte recovery from cardioplegic transport solution exposure.
Stem cells (Dayton, Ohio). 39(2):170-182 [DOI] 10.1002/stem.3296. [PMID] 33159685.
2020
Whole-Body Vibration Training Increases Stem/Progenitor Cell Circulation Levels and May Attenuate Inflammation.
Military medicine. 185(Suppl 1):404-412 [DOI] 10.1093/milmed/usz247. [PMID] 32074302.
2020
Tissue Engineering Clinical Council Roundtable Discussion: Opportunities and Challenges in Clinical Translation.
Tissue engineering. Part A. 26(3-4):113-119 [DOI] 10.1089/ten.tea.2019.0037. [PMID] 31977299.
2020
Therapeutic Use of Adipose-Derived Stromal Cells in a Murine Model of Acute Pancreatitis.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 24(1):67-75 [DOI] 10.1007/s11605-019-04411-w. [PMID] 31745900.
2020
Mesenchymal stem cell secretions improve donor heart function following ex vivo cold storage.
The Journal of thoracic and cardiovascular surgery. [DOI] 10.1016/j.jtcvs.2020.08.095. [PMID] 32981709.
2020
Allogeneic Mesenchymal Cell Therapy in Anthracycline-Induced Cardiomyopathy Heart Failure Patients: The CCTRN SENECA Trial.
JACC. CardioOncology. 2(4):581-595 [DOI] 10.1016/j.jaccao.2020.09.001. [PMID] 33403362.
2020
Distinct Factors Secreted by Adipose Stromal Cells Protect the Endothelium From Barrier Dysfunction and Apoptosis.
Frontiers in cell and developmental biology. 8 [DOI] 10.3389/fcell.2020.584653. [PMID] 33102487.
2020
Cardiac stem cell therapy among Clinics of Uncertain Regulatory Status (COURS): under-regulated, under-observed, incompletely understood.
Journal of translational medicine. 18(1) [DOI] 10.1186/s12967-020-02425-6. [PMID] 32678051.
2020
Arguments for a Different Regulatory Categorization and Framework for Stromal Vascular Fraction.
Stem cells and development. 29(5):257-262 [DOI] 10.1089/scd.2019.0096. [PMID] 31797749.
2020
Immune Dysregulation in HFpEF: A Target for Mesenchymal Stem/Stromal Cell Therapy.
Journal of clinical medicine. 9(1) [DOI] 10.3390/jcm9010241. [PMID] 31963368.
2019
Complementary Embryonic and Adult Cell Populations Enhance Myocardial Repair in Rat Myocardial Injury Model.
Stem cells international. 2019 [DOI] 10.1155/2019/3945850. [PMID] 31781239.
2019
Identifying Cancer Patients at Risk for Heart Failure Using Machine Learning Methods.
AMIA … Annual Symposium proceedings. AMIA Symposium. 2019:933-941 [PMID] 32308890.
View on: PubMed
2019
α’ formation kinetics and radiation induced segregation in neutron irradiated 14YWT nanostructured ferritic alloys.
Scientific reports. 9(1) [DOI] 10.1038/s41598-019-44508-5. [PMID] 31171811.
2018
Regenerative Medicine in the State of Florida: Letter Outlining the Florida Organization for Regenerative Medicine.
Stem cells translational medicine. 7(7):511-512 [DOI] 10.1002/sctm.18-0066. [PMID] 30403444.
2018
Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit+ Cardiac Stem Cells As Regenerative Therapy for Heart Failure).
Circulation research. 122(12):1703-1715 [DOI] 10.1161/CIRCRESAHA.118.312978. [PMID] 29703749.
2018
Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury.
Respiratory research. 19(1) [DOI] 10.1186/s12931-018-0812-1. [PMID] 29855321.
2018
Intentional polarity conversion of AlN epitaxial layers by oxygen.
Scientific reports. 8(1) [DOI] 10.1038/s41598-018-32489-w. [PMID] 30237522.
2018
Hypoxia-induced activin A diminishes endothelial cell vasculogenic activity.
Journal of cellular and molecular medicine. 22(1):173-184 [DOI] 10.1111/jcmm.13306. [PMID] 28834227.
2018
Rationale and Design of the SENECA (StEm cell iNjECtion in cAncer survivors) Trial.
American heart journal. 201:54-62 [DOI] 10.1016/j.ahj.2018.02.009. [PMID] 29910056.
2018
EMAPII Monoclonal Antibody Ameliorates Influenza A Virus-Induced Lung Injury.
Molecular therapy : the journal of the American Society of Gene Therapy. 26(8):2060-2069 [DOI] 10.1016/j.ymthe.2018.05.017. [PMID] 29910176.
2018
Cigarette Smoking Impairs Adipose Stromal Cell Vasculogenic Activity and Abrogates Potency to Ameliorate Ischemia.
Stem cells (Dayton, Ohio). 36(6):856-867 [DOI] 10.1002/stem.2813. [PMID] 29589872.
2018
Adipose-derived stem cell conditioned medium impacts asymptomatic peripheral neuromuscular denervation in the mutant superoxide dismutase (G93A) transgenic mouse model of amyotrophic lateral sclerosis.
Restorative neurology and neuroscience. 36(5):621-627 [DOI] 10.3233/RNN-180820. [PMID] 30010155.
2018
AMD3100 ameliorates cigarette smoke-induced emphysema-like manifestations in mice.
American journal of physiology. Lung cellular and molecular physiology. 315(3):L382-L386 [DOI] 10.1152/ajplung.00185.2018. [PMID] 29745251.
2018
Hypertension in pregnancy: Taking cues from pathophysiology for clinical practice.
Clinical cardiology. 41(2):220-227 [DOI] 10.1002/clc.22892. [PMID] 29485737.
2017
Transcriptional Networks in Single Perivascular Cells Sorted from Human Adipose Tissue Reveal a Hierarchy of Mesenchymal Stem Cells.
Stem cells (Dayton, Ohio). 35(5):1273-1289 [DOI] 10.1002/stem.2599. [PMID] 28233376.
2017
Oncostatin M and TNF-α Induce Alpha-1 Antitrypsin Production in Undifferentiated Adipose Stromal Cells.
Stem cells and development. 26(20):1468-1476 [DOI] 10.1089/scd.2017.0099. [PMID] 28825379.
2017
Mucosal Perfusion Preservation by a Novel Shapeable Tissue Expander for Oral Reconstruction.
Plastic and reconstructive surgery. Global open. 5(8) [DOI] 10.1097/GOX.0000000000001449. [PMID] 28894668.
2017
Human Adipose-Derived Stem Cells Suppress Elastase-Induced Murine Abdominal Aortic Inflammation and Aneurysm Expansion Through Paracrine Factors.
Cell transplantation. 26(2):173-189 [DOI] 10.3727/096368916X692212. [PMID] 27436185.
2017
Human adipose stromal cell therapy improves survival and reduces renal inflammation and capillary rarefaction in acute kidney injury.
Journal of cellular and molecular medicine. 21(7):1420-1430 [DOI] 10.1111/jcmm.13071. [PMID] 28455887.
2017
Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).
Circulation. 135(15):1417-1428 [DOI] 10.1161/CIRCULATIONAHA.116.025707. [PMID] 28209728.
2017
Cardiac Cell Therapy Evolving From Complex to Straightforward: Enabling Adoption and Affordability.
Circulation research. 121(10):1116-1118 [DOI] 10.1161/CIRCRESAHA.117.311947. [PMID] 29074527.
2017
Adipose stromal cells differentiation toward smooth muscle cell phenotype diminishes their vasculogenic activity due to induction of activin A secretion.
Journal of tissue engineering and regenerative medicine. 11(11):3145-3156 [DOI] 10.1002/term.2223. [PMID] 27633499.
2017
Adipose Stem Cell Function Maintained with Age: An Intra-Subject Study of Long-Term Cryopreserved Cells.
Aesthetic surgery journal. 37(4):454-463 [DOI] 10.1093/asj/sjw197. [PMID] 28364523.
2017
Electroacupuncture Promotes Central Nervous System-Dependent Release of Mesenchymal Stem Cells.
Stem cells (Dayton, Ohio). 35(5):1303-1315 [DOI] 10.1002/stem.2613. [PMID] 28299842.
2016
Surgical Therapies and Tissue Engineering: At the Intersection Between Innovation and Regulation.
Tissue engineering. Part A. 22(5-6):397-400 [DOI] 10.1089/ten.TEA.2016.0002. [PMID] 26895615.
2016
Therapeutic Potential of Adipose-Derived Therapeutic Factor Concentrate for Treating Critical Limb Ischemia.
Cell transplantation. 25(9):1623-1633 [PMID] 26525042.
View on: PubMed
2016
Prospective purification of perivascular presumptive mesenchymal stem cells from human adipose tissue: process optimization and cell population metrics across a large cohort of diverse demographics.
Stem cell research & therapy. 7 [DOI] 10.1186/s13287-016-0302-7. [PMID] 27029948.
2016
Pulmonary Retention of Adipose Stromal Cells Following Intravenous Delivery Is Markedly Altered in the Presence of ARDS.
Cell transplantation. 25(9):1635-1643 [PMID] 26609693.
View on: PubMed
2016
GDNF secreted from adipose-derived stem cells stimulates VEGF-independent angiogenesis.
Oncotarget. 7(24):36829-36841 [DOI] 10.18632/oncotarget.9208. [PMID] 27167204.
2016
Distinct Effects of Adipose-Derived Stem Cells and Adipocytes on Normal and Cancer Cell Hierarchy.
Molecular cancer research : MCR. 14(7):660-71 [DOI] 10.1158/1541-7786.MCR-16-0055. [PMID] 27097643.
2016
Corrigendum: Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis.
Scientific reports. 6 [DOI] 10.1038/srep20747. [PMID] 27079538.
2016
Human Adipose Stromal Cells Increase Survival and Mesenteric Perfusion Following Intestinal Ischemia and Reperfusion Injury.
Shock (Augusta, Ga.). 46(1):75-82 [DOI] 10.1097/SHK.0000000000000571. [PMID] 26796571.
2015
Adipose Stromal Cell Contact with Endothelial Cells Results in Loss of Complementary Vasculogenic Activity Mediated by Induction of Activin A.
Stem cells (Dayton, Ohio). 33(10):3039-51 [DOI] 10.1002/stem.2074. [PMID] 26037810.
2015
Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis.
Scientific reports. 5 [DOI] 10.1038/srep16953. [PMID] 26586020.
2015
Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
Journal of translational medicine. 13 [DOI] 10.1186/s12967-015-0422-3. [PMID] 25889857.
2015
Human adipose-derived stem cells ameliorate cigarette smoke-induced murine myelosuppression via secretion of TSG-6.
Stem cells (Dayton, Ohio). 33(2):468-78 [DOI] 10.1002/stem.1851. [PMID] 25329668.
2015
Intravenous xenogeneic transplantation of human adipose-derived stem cells improves left ventricular function and microvascular integrity in swine myocardial infarction model.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 86(2):E38-48 [DOI] 10.1002/ccd.25566. [PMID] 24905889.
2015
Memristive and neuromorphic behavior in a Li(x)CoO2 nanobattery.
Scientific reports. 5 [DOI] 10.1038/srep07761. [PMID] 25585693.
2014
Selective inhibition of pancreatic ductal adenocarcinoma cell growth by the mitotic MPS1 kinase inhibitor NMS-P715.
Molecular cancer therapeutics. 13(2):307-315 [DOI] 10.1158/1535-7163.MCT-13-0324. [PMID] 24282275.
2014
Regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy.
PloS one. 9(1) [DOI] 10.1371/journal.pone.0084671. [PMID] 24416262.
2014
Human adipose-derived stromal/stem cells protect against STZ-induced hyperglycemia: analysis of hASC-derived paracrine effectors.
Stem cells (Dayton, Ohio). 32(7):1831-42 [DOI] 10.1002/stem.1676. [PMID] 24519994.
2014
Adipose stromal cells differentiate along a smooth muscle lineage pathway upon endothelial cell contact via induction of activin A.
Circulation research. 115(9):800-9 [DOI] 10.1161/CIRCRESAHA.115.304026. [PMID] 25114097.
2014
Intracoronary and retrograde coronary venous myocardial delivery of adipose-derived stem cells in swine infarction lead to transient myocardial trapping with predominant pulmonary redistribution.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 83(1):E17-25 [DOI] 10.1002/ccd.24659. [PMID] 22972685.
2013
Dr. Sonia Skarlatos-leader, colleague, and friend: from vascular biology to gene therapy and the Cardiovascular Cell Therapy research network.
Human gene therapy. 24(11):896-8 [DOI] 10.1089/hum.2013.2518. [PMID] 24164236.
2013
Intramyocardial transplantation of human adipose-derived stromal cell and endothelial progenitor cell mixture was not superior to individual cell type transplantation in improving left ventricular function in rats with myocardial infarction.
International journal of cardiology. 164(2):205-11 [DOI] 10.1016/j.ijcard.2011.06.128. [PMID] 21794931.
2013
Phase II clinical research design in cardiology: learning the right lessons too well: observations and recommendations from the Cardiovascular Cell Therapy Research Network (CCTRN).
Circulation. 127(15):1630-5 [DOI] 10.1161/CIRCULATIONAHA.112.000779. [PMID] 23588961.
2013
Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT).
Cytotherapy. 15(6):641-8 [DOI] 10.1016/j.jcyt.2013.02.006. [PMID] 23570660.
2012
Resident Endothelial Progenitor Cells From Human Placenta Have Greater Vasculogenic Potential Than Circulating Endothelial Progenitor Cells From Umbilical Cord Blood.
Cell medicine. 2(3):85-96 [DOI] 10.3727/215517911X617888. [PMID] 27004134.
2012
Morphologic changes in photodamaged organotypic human skin culture after treatment of autologous adipose-derived stromal cells.
The Journal of craniofacial surgery. 23(3):805-11 [DOI] 10.1097/SCS.0b013e31824e6c87. [PMID] 22565925.
2012
Electroanatomic remodeling of the left stellate ganglion after myocardial infarction.
Journal of the American College of Cardiology. 59(10):954-61 [DOI] 10.1016/j.jacc.2011.11.030. [PMID] 22381432.
2012
Autologous stromal vascular fraction therapy for rheumatoid arthritis: rationale and clinical safety.
International archives of medicine. 5 [DOI] 10.1186/1755-7682-5-5. [PMID] 22313603.
2011
Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking.
American journal of respiratory and critical care medicine. 183(2):215-25 [DOI] 10.1164/rccm.201001-0126OC. [PMID] 20709815.
2011
Autologous bone marrow mononuclear cell therapy is safe and promotes amputation-free survival in patients with critical limb ischemia.
Journal of vascular surgery. 53(6):1565-74.e1 [DOI] 10.1016/j.jvs.2011.01.074. [PMID] 21514773.
2011
Potential of gallium-based leads for cardiac rhythm management devices.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2011:341-4 [DOI] 10.1109/IEMBS.2011.6090113. [PMID] 22254318.
2011
The creation of an in vitro adipose tissue that contains a vascular-adipocyte complex.
Biomaterials. 32(36):9667-76 [DOI] 10.1016/j.biomaterials.2011.08.090. [PMID] 21959010.
2010
Adipose tissue progenitor cells directly interact with endothelial cells to induce vascular network formation.
Tissue engineering. Part A. 16(9):2953-66 [DOI] 10.1089/ten.TEA.2009.0635. [PMID] 20486792.
2010
Development of a porcine delayed wound-healing model and its use in testing a novel cell-based therapy.
International journal of radiation oncology, biology, physics. 78(3):888-96 [DOI] 10.1016/j.ijrobp.2010.05.002. [PMID] 20708345.
2010
Muscle-derived Gr1(dim)CD11b(+) cells enhance neovascularization in an ischemic hind limb mouse model.
Blood. 116(9):1623-6 [DOI] 10.1182/blood-2009-08-237040. [PMID] 20516368.
2010
Therapeutic potential of adipose-derived stem cells in vascular growth and tissue repair.
Current opinion in organ transplantation. 15(1):86-91 [DOI] 10.1097/MOT.0b013e328334f074. [PMID] 19949335.
2009
LifeShirt acquisition system to monitor ECG from ambulatory swine and the implementation of an arrhythmia detection algorithm.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2009:4820-3 [DOI] 10.1109/IEMBS.2009.5332632. [PMID] 19963627.
2009
Interphase FISH demonstrates that human adipose stromal cells maintain a high level of genomic stability in long-term culture.
Stem cells and development. 18(5):717-24 [DOI] 10.1089/scd.2008.0255. [PMID] 18754715.
2009
IFATS collection: The conditioned media of adipose stromal cells protect against hypoxia-ischemia-induced brain damage in neonatal rats.
Stem cells (Dayton, Ohio). 27(2):478-88 [DOI] 10.1634/stemcells.2008-0333. [PMID] 19023032.
2009
IFATS collection: Human adipose tissue-derived stem cells induce angiogenesis and nerve sprouting following myocardial infarction, in conjunction with potent preservation of cardiac function.
Stem cells (Dayton, Ohio). 27(1):230-7 [DOI] 10.1634/stemcells.2008-0273. [PMID] 18772313.
2009
Adipose stromal cells and platelet-rich plasma therapies synergistically increase revascularization during wound healing.
Plastic and reconstructive surgery. 123(2 Suppl):56S-64S [DOI] 10.1097/PRS.0b013e318191be2d. [PMID] 19182664.
2009
Adipose stromal cells-secreted neuroprotective media against neuronal apoptosis.
Neuroscience letters. 462(1):76-9 [DOI] 10.1016/j.neulet.2009.06.054. [PMID] 19549558.
2009
Adipose stromal cells-conditional medium protected glutamate-induced CGNs neuronal death by BDNF.
Neuroscience letters. 452(3):238-40 [DOI] 10.1016/j.neulet.2009.01.025. [PMID] 19348731.
2009
Expression of RAC2 in endothelial cells is required for the postnatal neovascular response.
Experimental cell research. 315(2):248-63 [PMID] 19123268.
View on: PubMed
2009
Robust functional vascular network formation in vivo by cooperation of adipose progenitor and endothelial cells.
Circulation research. 104(12):1410-20 [DOI] 10.1161/CIRCRESAHA.108.190926. [PMID] 19443841.
2009
The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation.
Endocrinology. 150(10):4552-61 [DOI] 10.1210/en.2009-0236. [PMID] 19574402.
2009
White adipose tissue cells are recruited by experimental tumors and promote cancer progression in mouse models.
Cancer research. 69(12):5259-66 [DOI] 10.1158/0008-5472.CAN-08-3444. [PMID] 19491274.
2008
A central role for hepatocyte growth factor in adipose tissue angiogenesis.
American journal of physiology. Endocrinology and metabolism. 294(2):E336-44 [PMID] 18073323.
View on: PubMed
2008
A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilize endothelial networks.
Circulation research. 102(1):77-85 [PMID] 17967785.
View on: PubMed
2008
Adipose stromal/stem cells: basic and translational advances: the IFATS collection.
Stem cells (Dayton, Ohio). 26(10):2664-5 [DOI] 10.1634/stemcells.2008-0927. [PMID] 18818434.
2008
Coronary venous retroperfusion: an old concept, a new approach.
Journal of applied physiology (Bethesda, Md. : 1985). 104(5):1266-72 [DOI] 10.1152/japplphysiol.00063.2008. [PMID] 18292303.
2008
IFATS collection: Adipose stromal cell differentiation is reduced by endothelial cell contact and paracrine communication: role of canonical Wnt signaling.
Stem cells (Dayton, Ohio). 26(10):2674-81 [DOI] 10.1634/stemcells.2008-0277. [PMID] 18669909.
2008
IFATS collection: Combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells.
Stem cells (Dayton, Ohio). 26(10):2735-45 [DOI] 10.1634/stemcells.2008-0212. [PMID] 18583538.
2008
In vitro clonal analysis of murine pluripotent stem cells isolated from skeletal muscle and adipose stromal cells.
Experimental hematology. 36(2):224-34 [PMID] 18023524.
View on: PubMed
2008
Transgenic model of smooth muscle cell cycle reentry: expression pattern of the collageneous matrix.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 17(2):72-80 [DOI] 10.1016/j.carpath.2007.07.003. [PMID] 18329551.
2007
Urokinase gene transfer augments angiogenesis in ischemic skeletal and myocardial muscle.
Molecular therapy : the journal of the American Society of Gene Therapy. 15(11):1939-46 [PMID] 17653104.
View on: PubMed
2007
Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization.
Stem cells (Dayton, Ohio). 25(12):3234-43 [PMID] 17901400.
View on: PubMed
2007
Acute myocardial infarction in swine rapidly and selectively releases highly proliferative endothelial colony forming cells (ECFCs) into circulation.
Cell transplantation. 16(9):887-97 [PMID] 18293887.
View on: PubMed
2006
[Adipose stromal cells–plastic type of cells with high therapeutic potential].
Tsitologiia. 48(2):83-94 [PMID] 16737175.
View on: PubMed
2006
[Adipose tissue stromal cells — multipotent cells with therapeutic potential for stimulation of angiogenesis in tissue ischemia].
Kardiologiia. 46(6):53-63 [PMID] 16883224.
View on: PubMed
2006
Adipose tissue production of hepatocyte growth factor contributes to elevated serum HGF in obesity.
American journal of physiology. Endocrinology and metabolism. 291(4):E843-8 [PMID] 16757549.
View on: PubMed
2006
Endothelial-monocyte-activating polypeptide II induces migration of endothelial progenitor cells via the chemokine receptor CXCR3.
Experimental hematology. 34(8):1125-32 [PMID] 16863920.
View on: PubMed
2006
Vascular injury response in mice is dependent on genetic background.
American journal of physiology. Heart and circulatory physiology. 290(3):H1307-10 [PMID] 16214836.
View on: PubMed
2005
Stent-based nitric oxide delivery reducing neointimal proliferation in a porcine carotid overstretch injury model.
Cardiovascular and interventional radiology. 28(1):60-5 [PMID] 15719180.
View on: PubMed
2005
Enhancing myocardial plasmid expression by retrograde coronary venous delivery.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 65(4):528-34 [PMID] 16003788.
View on: PubMed
2005
Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials.
Circulation. 112(9 Suppl):I150-6 [PMID] 16159808.
View on: PubMed
2005
Angiostatin is negatively associated with coronary collateral growth in patients with coronary artery disease.
American journal of physiology. Heart and circulatory physiology. 288(5):H2042-6 [PMID] 15840902.
View on: PubMed
2005
Balancing luminal size and smooth muscle proliferation–a key control point in atherosclerosis and arteriogenesis.
EXS. (94):193-205 [PMID] 15617480.
View on: PubMed
2005
Clonal multilineage differentiation of murine common pluripotent stem cells isolated from skeletal muscle and adipose stromal cells.
Annals of the New York Academy of Sciences. 1044:183-200 [PMID] 15958712.
View on: PubMed
2004
Cellular approaches to tissue repair in cardiovascular disease: the more we know, the more there is to learn.
American journal of physiology. Heart and circulatory physiology. 287(2):H458-63 [PMID] 15277189.
View on: PubMed
2004
Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia.
Circulation. 110(16):2467-75 [PMID] 15477407.
View on: PubMed
2004
Exercise acutely increases circulating endothelial progenitor cells and monocyte-/macrophage-derived angiogenic cells.
Journal of the American College of Cardiology. 43(12):2314-8 [PMID] 15193699.
View on: PubMed
2004
P38 MAPK mediates myocardial proinflammatory cytokine production and endotoxin-induced contractile suppression.
Shock (Augusta, Ga.). 21(2):170-4 [PMID] 14752292.
View on: PubMed
2004
Preconditioning: evolution of basic mechanisms to potential therapeutic strategies.
Shock (Augusta, Ga.). 21(3):195-209 [PMID] 14770032.
View on: PubMed
2004
Reduced pericardial levels of endostatin correlate with collateral development in patients with ischemic heart disease.
Journal of the American College of Cardiology. 43(8):1383-7 [PMID] 15093871.
View on: PubMed
2004
Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells.
Circulation. 109(10):1292-8 [PMID] 14993122.
View on: PubMed
2003
Vascular ligation response is independent of p107: stressing the role of the related p130.
American journal of physiology. Heart and circulatory physiology. 285(2):H915-8 [PMID] 12860570.
View on: PubMed
2003
Role of pRb family members in injured carotid arteries.
Journal of vascular research. 40(1):83-4 [PMID] 12644729.
View on: PubMed
2003
Peripheral blood “endothelial progenitor cells” are derived from monocyte/macrophages and secrete angiogenic growth factors.
Circulation. 107(8):1164-9 [PMID] 12615796.
View on: PubMed
2003
Obesity is associated with increased levels of circulating hepatocyte growth factor.
Journal of the American College of Cardiology. 41(8):1408-13 [PMID] 12706940.
View on: PubMed
2003
A novel percutaneous technique for accessing the normal pericardium: a single-center successful experience of 53 porcine procedures.
The Journal of invasive cardiology. 15(1):13-7 [PMID] 12499522.
View on: PubMed
2003
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.
Circulation. 108(15):1772-8 [PMID] 14557340.
View on: PubMed
2003
Widespread regional myocardial transfection by plasmid encoding Del-1 following retrograde coronary venous delivery.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 58(2):207-11 [PMID] 12552546.
View on: PubMed
2003
Intrapericardial ethanol delivery inhibits neointimal proliferation after porcine coronary overstretch.
Journal of the Chinese Medical Association : JCMA. 66(11):637-42 [PMID] 14768850.
View on: PubMed
2003
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I.
Circulation. 108(14):1664-72 [PMID] 14530185.
View on: PubMed
2002
Stent-based approach for ventricle-to-coronary artery bypass.
Circulation. 106(8):1000-6 [PMID] 12186807.
View on: PubMed
2002
Smooth muscle-specific expression of SV40 large TAg induces SMC proliferation causing adaptive arterial remodeling.
American journal of physiology. Heart and circulatory physiology. 283(6):H2714-24 [PMID] 12388294.
View on: PubMed
2002
Augmentation of intrapericardial nitric oxide level by a prolonged-release nitric oxide donor reduces luminal narrowing after porcine coronary angioplasty.
Circulation. 105(23):2779-84 [PMID] 12057994.
View on: PubMed
2002
Direct evidence for the importance of p130 in injury response and arterial remodeling following carotid artery ligation.
Cardiovascular research. 54(3):676-83 [PMID] 12031714.
View on: PubMed
2001
Advantages of short-lived positron-emitting radioisotopes for intracoronary radiation therapy with liquid-filled balloons to prevent restenosis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(9):1375-83 [PMID] 11535728.
View on: PubMed
2001
Improved laser-assisted vascular tissue fusion using light-activated surgical adhesive in a porcine model.
Biomedical sciences instrumentation. 37:451-6 [PMID] 11347433.
View on: PubMed
2001
Liquid-filled balloon brachytherapy using (68)Ga is effective and safe because of the short 68-minute half-life: results of a feasibility study in the porcine coronary overstretch model.
Circulation. 103(13):1793-8 [PMID] 11282912.
View on: PubMed
2000
Differences in the effects of HMG-CoA reductase inhibitors on proliferation and viability of smooth muscle cells in culture.
Atherosclerosis. 150(2):331-41 [PMID] 10856525.
View on: PubMed
2000
Intrapericardial paclitaxel delivery inhibits neointimal proliferation and promotes arterial enlargement after porcine coronary overstretch.
Circulation. 102(13):1575-81 [PMID] 11004150.
View on: PubMed
2000
p75(NTR) mediates neurotrophin-induced apoptosis of vascular smooth muscle cells.
The American journal of pathology. 157(4):1247-58 [PMID] 11021829.
View on: PubMed
2000
Studies of renal injury III: lipid-induced nephropathy in type II diabetes.
Kidney international. 57(1):92-104 [PMID] 10620191.
View on: PubMed
1999
Pharmacokinetics and consistency of pericardial delivery directed to coronary arteries: direct comparison with endoluminal delivery.
Clinical cardiology. 22(1 Suppl 1):I10-6 [PMID] 9929762.
View on: PubMed
1999
NGF activates similar intracellular signaling pathways in vascular smooth muscle cells as PDGF-BB but elicits different biological responses.
Arteriosclerosis, thrombosis, and vascular biology. 19(4):1041-50 [PMID] 10195934.
View on: PubMed
1999
Hyperplasia in multiple smooth muscle tissues in transgenic mice expressing a temperature-sensitive SV40 T-antigen under the control of smooth muscle alpha-actin regulatory sequences.
Oncogene. 18(25):3773-82 [PMID] 10391686.
View on: PubMed
1999
Efficient in vivo catheter-based pericardial gene transfer mediated by adenoviral vectors.
Clinical cardiology. 22(1 Suppl 1):I23-9 [PMID] 9929764.
View on: PubMed
1999
Establishment of a clinically correlated human pericardial fluid bank: evaluation of intrapericardial diagnostic potential.
Clinical cardiology. 22(1 Suppl 1):I40-2 [PMID] 9929767.
View on: PubMed
1998
Gene therapy for restenosis: getting nearer the heart of the matter.
Circulation research. 82(3):295-305 [PMID] 9486657.
View on: PubMed
1998
Heparin responsiveness in vitro as a prognostic tool for vascular graft stenosis: a tale of two cell types?
Circulation. 97(25):2486-90 [PMID] 9657465.
View on: PubMed
1997
Activation of MAP kinase in vivo follows balloon overstretch injury of porcine coronary and carotid arteries.
Circulation research. 81(6):904-10 [PMID] 9400370.
View on: PubMed
1997
Effect of atherosclerosis on transmural convection an arterial ultrastructure. Implications for local intravascular drug delivery.
Arteriosclerosis, thrombosis, and vascular biology. 17(12):3365-75 [PMID] 9437181.
View on: PubMed
1996
Vascular repair mechanisms after directional atherectomy or percutaneous transluminal coronary angioplasty in atherosclerotic rabbit iliac arteries.
American heart journal. 132(1 Pt 1):13-22 [PMID] 8701854.
View on: PubMed
1996
Microspheres.
Seminars in interventional cardiology : SIIC. 1(1):48-50 [PMID] 9552493.
View on: PubMed
1996
Methods of local gene delivery to vascular tissues.
Seminars in interventional cardiology : SIIC. 1(3):215-23 [PMID] 9552514.
View on: PubMed
1996
Human surfactant protein A enhances attachment of Pneumocystis carinii to rat alveolar macrophages.
American journal of respiratory cell and molecular biology. 14(3):232-8 [PMID] 8845173.
View on: PubMed
1996
Microparticle deposition in periarterial microvasculature and intramural dissections after porous balloon delivery into atherosclerotic vessels: quantitation and localization by confocal scanning laser microscopy.
American heart journal. 131(5):892-8 [PMID] 8615307.
View on: PubMed
1995
Local delivery of biodegradable microparticles containing colchicine or a colchicine analogue: effects on restenosis and implications for catheter-based drug delivery.
Journal of the American College of Cardiology. 26(6):1549-57 [PMID] 7594084.
View on: PubMed
1995
Pharmacokinetics of adenoviral vector-mediated gene delivery to vascular smooth muscle cells: modulation by poloxamer 407 and implications for cardiovascular gene therapy.
Human gene therapy. 6(1):41-53 [PMID] 7703286.
View on: PubMed
1995
Regional and arterial localization of radioactive microparticles after local delivery by unsupported or supported porous balloon catheters.
American heart journal. 129(5):852-9 [PMID] 7732972.
View on: PubMed
1995
Vascular injury, repair, and restenosis after percutaneous transluminal angioplasty in the atherosclerotic rabbit.
Circulation. 92(10):2995-3005 [PMID] 7586270.
View on: PubMed
1994
Biodegradable microspheres containing a colchicine analogue inhibit DNA synthesis in vascular smooth muscle cells.
Circulation. 89(5):1929-33 [PMID] 8181114.
View on: PubMed
1993
8-Methoxypsoralen and longwave ultraviolet irradiation are a novel antiproliferative combination for vascular smooth muscle.
Circulation. 87(1):184-91 [PMID] 8419006.
View on: PubMed
1993
Effects of thiol protease inhibitors on cell cycle and proliferation of vascular smooth muscle cells in culture.
Circulation research. 72(2):413-23 [PMID] 8418992.
View on: PubMed
1993
Methods and devices for local drug delivery in coronary and peripheral arteries.
Trends in cardiovascular medicine. 3(5):163-70 [DOI] 10.1016/1050-1738(93)90001-M. [PMID] 21244928.
1991
Direct intraarterial wall injection of microparticles via a catheter: a potential drug delivery strategy following angioplasty.
American heart journal. 122(4 Pt 1):1136-40 [PMID] 1833964.
View on: PubMed
1991
Vascular smooth muscle. A review of the molecular basis of contractility.
Circulation. 83(2):382-90 [PMID] 1991362.
View on: PubMed
1989
Current concepts of left ventricular pseudoaneurysm: pathophysiology, therapy, and diagnostic imaging methods.
Clinical cardiology. 12(9):531-40 [PMID] 2676292.
View on: PubMed
1989
Molecular cardiology: new avenues for the diagnosis and treatment of cardiovascular disease.
Journal of the American College of Cardiology. 13(2):265-82 [PMID] 2643653.
View on: PubMed
1986
Effects of intraoperative glucose on protein catabolism and plasma glucose levels in patients with supratentorial tumors.
Anesthesiology. 64(4):453-9 [PMID] 3516017.
View on: PubMed

Grants

Dec 2020 ACTIVE
IPA for Stephanie Merfeld-Clauss
Role: Other
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Mar 2019 ACTIVE
Combination of Secretome from Electrically Stimulated ASCs and Injectable ECM Scaffolds as Potential SCI Therapy
Role: Project Manager
Funding: NATL INST OF HLTH NINDS
Jan 2019 ACTIVE
Miscellaneous Donors Project
Role: Principal Investigator
Funding: MISCELLANEOUS DONORS
Dec 2018 – Nov 2020
IPA for Stephanie Merfeld-Clauss
Role: Other
Funding: US DEPT OF VET AFF GAINESVILLE MED CTR
Jun 2018 ACTIVE
OR-DRPD-ROF2018: Perfusable Magnetic Cryoprotecting Agents for Heart Biobanking
Role: Co-Investigator
Funding: UF RESEARCH
Sep 2017 ACTIVE
Women's Ischemia Trial to Reduce Events in Non-Obstructive CAD (WARRIOR)
Role: Project Manager
Funding: US ARMY MED RES ACQUISITION
Jul 2017 – Jun 2019
Adipose Stem Cell Secretome Provides Novel Functional and Molecular Cardiac Preservation
Role: Principal Investigator
Funding: AMER HEART ASSOCIATION

Teaching Profile

Courses Taught
2019-2021
IDH3931 Interdisciplinary Junior Honors
2018
MDT7090 Elective Topics

Contact Details

Phones:
Business:
(352) 294-8620
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