Carl J Pepine, M.D.
Professor Of Medicine
About Carl J Pepine
Carl J. Pepine, MD, is a doctor in the Division of Cardiovascular Medicine at the University of Florida College of Medicine. He graduated from the University of Pittsburgh in 1962 with his bachelor’s degree.
As he started medical school at Rutgers in New Jersey with his MD in 1966, Pepine stayed in the northeast for his internship at Allegheny General Hospital, a University of Pittsburgh affiliate. His two residencies were at Jefferson Medical College Hospital and Regional Naval Medical Center. He completed both fellowships in 1971 and became board certified in Internal Medicine and the subspeciality of Cardiovascular Disease.
He is currently a principal investigator of many NIH- and industry-funded research projects on cardiovascular disease in women, IHD, hypertension, heart failure, and cell-based therapy, with continuous peer-reviewed federal research funding (DoD, NIH, VA Merit) for over 40 years.
Pepine served as Chief of the UF Division of Cardiovascular Medicine from 1998–2008 and Chief of Cardiology, VA Medical Center, from 1978–1994. He has published more than 1,100 scientific articles, has edited 6 textbooks, and has been on the editorial boards of all major cardiovascular journals. He is the founding editor of Cardiology Today and Editor-in-Chief for American Heart Journal Plus: Cardiology Research and Practice. Pepine is currently the co-director of CTSI Multi-site Study Support Team at the National Center for Research.
Accomplishments
Wenger Award for Excellence in Medical research and Leadership
2019
·
National Coalition for Women with Heart Disease
Bernadine Healy Leadership in Women’s Cardiovascular Disease Award
2018
·
American College of Cardiology
Lifetime Achievement Award
2010
·
University of Florida
Gifted Scientist Award
2009
·
Florida Chapter, American College of Cardiology
Distinguished International Educator
2005
·
University of Florida
President
2003-2004
·
American College of Cardiology
Eminent Scholar Chair in Cardiovascular Research (UF)
2001-2008
·
American Heart Association (AHA) – Suncoast Chapter, Inc.
Gifted Teacher Award
2001
·
Florida Chapter, American College of Cardiology
Research Foundation Professorship Award
1999-2001
·
University of Florida
Elected to Association of University Cardiologists (AUC)
1998
·
Association of University Cardiologists
Theodore E. Woodward Award
1998
·
American Clinical and Climatological Association (ACCA)
Paul Dudley White Award
1991
·
Association of Military Surgeons of the United States
President
1986-1987
·
Florida Chapter, Amercian College of Cardiology
Elected to the American Society for Clinical Investigation (ASCI)
1982
·
American Society for Clinical Investigation
Outstanding Young Men of America
1972
·
Outstanding Young Men of America
Teaching Profile
Courses Taught
2014
GMS6335 Tissue Engineering
Board Certifications
-
Cardiovascular DiseaseAmerican Board of Internal Medicine
-
DiplomateAmerican Board of Internal Medicine
-
DiplomateNational Board of Medical Examiners
Clinical Profile
Specialties
- Cardiology
Areas of Interest
- Cardiomyopathy
- Coronary heart disease
- Essential hypertension
Research Profile
My career has focused on improving our understanding of mechanisms underlying ischemic heart disease (IHD) and related adverse outcomes. I have conducted extensive investigations in coronary artery disease (CAD), hypertension, treatment resistant hypertension, vascular biology, and therapeutic applications related to vascular dysfunction. My work has centered on how IHD becomes manifest with and without large coronary artery obstructive disease (CAD). Much of this work is concentrated in women with known or suspect IHD. A major goal of clinical research is development of actionable information of sufficient power to alter medical care and improve patient health by information obtained through performance of clinical trials. To this end, I conceived and led the first randomized controlled international mega-trial of blood pressure control for patients with CAD (INVEST). My experience also includes being a principal investigator (PI) in multiple NHLBI-funded projects [Women’s Ischemia Syndrome Evaluation (WISE), WISE-CVD, WISE HFpEF, MayWEST, Asymptomatic Cardiac Ischemia Pilot (ACIP), Psychophysiologic Interventions of Myocardial Ischemia (PIMI), Bypass Angioplasty Revascularization Investigation 2-Diabetes Trial (BARI2D), etc.] and many other industry-sponsored studies. More recently I have been working in cardiovascular recovery and regeneration with cell based therapies as a PI in the NHLBI Cardiovascular Cell Therapy Network (CCTRN)- 1 and 2, as well as studies funded by the the cell and gene biomedical industry.
Open Researcher and Contributor ID (ORCID)
0000-0002-6011-681X
Areas of Interest
- Cardiovascular Cell Therapy
- Heart Disease in Women
- Heart Failure
- Hypertension
- Ischemic Heart Disease
Publications
Academic Articles
2024
Angiogenic Gene Therapy for Refractory Angina: Results of the EXACT Phase 2 Trial.
Circulation. Cardiovascular interventions.
17(5)
[DOI] 10.1161/CIRCINTERVENTIONS.124.014054.
[PMID] 38696284.
2024
Arterial stiffness assessment in coronary microvascular dysfunction and heart failure with preserved ejection fraction: An initial report from the WISE-CVD continuation study.
American heart journal plus : cardiology research and practice.
41
[DOI] 10.1016/j.ahjo.2024.100390.
[PMID] 38600957.
2024
Comparison of risk profiles of participants in the Women’s IschemiA TRial to Reduce events In non-ObstRuctive CAD (WARRIOR) trial, using Coronary Computed Tomography Angiography vs Invasive Coronary Angiography.
Progress in cardiovascular diseases.
84:90-93
[DOI] 10.1016/j.pcad.2024.03.008.
[PMID] 38547955.
2024
Contributors to high left ventricular ejection fraction in women with ischemia and no obstructive coronary artery disease: Results from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) Study.
American heart journal.
278:41-47
[DOI] 10.1016/j.ahj.2024.08.021.
[PMID] 39233211.
2024
Elevated high-density lipoprotein cholesterol and adverse outcomes in women with symptoms of ischemic heart disease.
American heart journal plus : cardiology research and practice.
40
[DOI] 10.1016/j.ahjo.2024.100376.
[PMID] 38510502.
2024
Endogenous androgens, coronary atheroma and remodeling in women with suspected ischemic heart disease: A report from the Women’s Ischemia Syndrome Evaluation (WISE) study.
American heart journal plus : cardiology research and practice.
43
[DOI] 10.1016/j.ahjo.2024.100411.
[PMID] 38873103.
2024
Evaluation of coronary microvascular dysfunction using magnetocardiography: A new application to an old technology.
American heart journal plus : cardiology research and practice.
44
[DOI] 10.1016/j.ahjo.2024.100424.
[PMID] 39108843.
2024
Hospitalization after hydroxychloroquine initiation in patients with heart failure with preserved ejection fraction and autoimmune disease.
Journal of internal medicine.
296(5):399-409
[DOI] 10.1111/joim.20004.
[PMID] 39193799.
2024
Identifying Potential Factors Associated With Racial Disparities in COVID-19 Outcomes: Retrospective Cohort Study Using Machine Learning on Real-World Data.
JMIR public health and surveillance.
10
[DOI] 10.2196/54421.
[PMID] 39326040.
2024
Impact of epicardial fat on coronary vascular function, cardiac morphology, and cardiac function in women with suspected INOCA.
European heart journal. Cardiovascular Imaging.
25(10):1360-1366
[DOI] 10.1093/ehjci/jeae203.
[PMID] 39129200.
2024
Initial Antihypertensive Prescribing in Relation to Blood Pressure Among Florida Medicaid and Medicare Recipients in the OneFlorida+ Research Consortium.
Hypertension (Dallas, Tex. : 1979).
81(2):e7-e9
[DOI] 10.1161/HYPERTENSIONAHA.123.21901.
[PMID] 38232142.
2024
Myocardial ischaemic syndromes: a new nomenclature to harmonize evolving international clinical practice guidelines.
European heart journal.
45(36):3701-3706
[DOI] 10.1093/eurheartj/ehae278.
[PMID] 39211956.
2024
Myocardial Ischemic Syndromes: A New Nomenclature to Harmonize Evolving International Clinical Practice Guidelines.
Circulation.
150(20):1631-1637
[DOI] 10.1161/CIRCULATIONAHA.123.065656.
[PMID] 39210827.
2024
Pericardial fat volume is related to endothelial-mediated coronary blood flow in women with suspected coronary microvascular dysfunction. A report from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) study.
American heart journal plus : cardiology research and practice.
40
[DOI] 10.1016/j.ahjo.2024.100379.
[PMID] 38586431.
2024
Physiology and functional significance of the coronary microcirculation: An overview of its implications in health and disease.
American heart journal plus : cardiology research and practice.
40
[DOI] 10.1016/j.ahjo.2024.100381.
[PMID] 38586427.
2024
Racial/ethnic disparities, artificial intelligence, and cutting-edge research: Proceedings from the 2023 Florida cardio-oncology symposium.
American heart journal plus : cardiology research and practice.
46
[DOI] 10.1016/j.ahjo.2024.100469.
[PMID] 39431118.
2024
Recipe for Heart Health: A Randomized Crossover Trial on Cardiometabolic Effects of Extra Virgin Olive Oil Within a Whole-Food Plant-Based Vegan Diet.
Journal of the American Heart Association.
13(15)
[DOI] 10.1161/JAHA.124.035034.
[PMID] 39045758.
2024
Single Nucleotide Polymorphisms in Coronary Microvascular Dysfunction.
Journal of the American Heart Association.
13(4)
[DOI] 10.1161/JAHA.123.032137.
[PMID] 38348798.
2024
Towards real-time myocardial infarction diagnosis: a convergence of machine learning and ion-exchange membrane technologies leveraging miRNA signatures.
Lab on a chip.
24(23):5203-5214
[DOI] 10.1039/d4lc00640b.
[PMID] 39415669.
2023
An international perspective on low-dose aspirin for the primary prevention of myocardial infarction.
International journal of cardiology.
373:17-22
[DOI] 10.1016/j.ijcard.2022.11.036.
[PMID] 36442672.
2023
ANOCA/INOCA/MINOCA: Open artery ischemia.
American heart journal plus : cardiology research and practice.
26
[DOI] 10.1016/j.ahjo.2023.100260.
[PMID] 37064505.
2023
Association of abnormal electrocardiography response on dobutamine stress echocardiogram with longer-term major adverse cardiovascular events in women with symptoms of ischemic heart disease.
Cardiovascular diagnosis and therapy.
13(6):948-955
[DOI] 10.21037/cdt-23-296.
[PMID] 38162097.
2023
Association of Coronary Artery Dominance With Long-term Outcomes in Female Patients With Suspected Ischemia but Nonobstructive Coronary Artery Disease.
Journal of the Society for Cardiovascular Angiography & Interventions.
2(5)
[DOI] 10.1016/j.jscai.2023.101064.
[PMID] 39132402.
2023
Autoimmune rheumatic diseases in women with coronary microvascular dysfunction: a report from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) project.
Frontiers in cardiovascular medicine.
10
[DOI] 10.3389/fcvm.2023.1155914.
[PMID] 37324629.
2023
Chronic rheumatologic disorders and cardiovascular disease risk in women.
American heart journal plus : cardiology research and practice.
27
[DOI] 10.1016/j.ahjo.2023.100267.
[PMID] 38511090.
2023
Circulating Biomarkers in Coronary Microvascular Dysfunction.
Journal of the American Heart Association.
12(12)
[DOI] 10.1161/JAHA.122.029341.
[PMID] 37301749.
2023
Clinically stable covid-19 patients presenting to acute unscheduled episodic care venues have increased risk of hospitalization: secondary analysis of a randomized control trial.
BMC infectious diseases.
23(1)
[DOI] 10.1186/s12879-023-08295-9.
[PMID] 37189091.
2023
Comparison of the effectiveness and safety of 2 aspirin doses in secondary prevention of cardiovascular outcomes in patients with chronic kidney disease: A subgroup analysis of ADAPTABLE.
American heart journal.
264:31-39
[DOI] 10.1016/j.ahj.2023.06.001.
[PMID] 37290700.
2023
Dietary Composition, Angiographic Coronary Disease, and Cardiovascular Outcomes in the WISE Study (Women’s Ischemia Syndrome Evaluation).
Journal of clinical medicine.
12(24)
[DOI] 10.3390/jcm12247762.
[PMID] 38137831.
2023
Effectiveness and Safety of Enteric-Coated vs Uncoated Aspirin in Patients With Cardiovascular Disease: A Secondary Analysis of the ADAPTABLE Randomized Clinical Trial.
JAMA cardiology.
8(11):1061-1069
[DOI] 10.1001/jamacardio.2023.3364.
[PMID] 37792369.
2023
Evolving Management Paradigm for Stable Ischemic Heart Disease Patients: JACC Review Topic of the Week.
Journal of the American College of Cardiology.
81(5):505-514
[DOI] 10.1016/j.jacc.2022.08.814.
[PMID] 36725179.
2023
EXACT Trial: Results of the Phase 1 Dose-Escalation Study.
Circulation. Cardiovascular interventions.
16(8)
[DOI] 10.1161/CIRCINTERVENTIONS.123.012997.
[PMID] 37503661.
2023
Fitness attenuates long-term cardiovascular outcomes in women with ischemic heart disease and metabolic syndrome.
American journal of preventive cardiology.
14
[DOI] 10.1016/j.ajpc.2023.100498.
[PMID] 37181803.
2023
Heart and brain interactions: is small vessel disease a link?
European heart journal.
44(2):126-128
[DOI] 10.1093/eurheartj/ehac570.
[PMID] 36367735.
2023
High-throughput screening for prescribing cascades among real world statin initiators.
Pharmacoepidemiology and drug safety.
32(7):773-782
[DOI] 10.1002/pds.5607.
[PMID] 36880251.
2023
Host-Microbiota Communication in Spontaneously Hypertensive Rats Generates Unique IgA-Coated Gut Microbes.
Journal of the American Heart Association.
12(4)
[DOI] 10.1161/JAHA.122.027918.
[PMID] 36752270.
2023
Influence of Butyrate on Impaired Gene Expression in Colon from Patients with High Blood Pressure.
International journal of molecular sciences.
24(3)
[DOI] 10.3390/ijms24032650.
[PMID] 36768972.
2023
Initial Antihypertensive Regimens in Newly Treated Patients: Real World Evidence From the OneFlorida+ Clinical Research Network.
Journal of the American Heart Association.
12(1)
[DOI] 10.1161/JAHA.122.026652.
[PMID] 36565195.
2023
Latest from the WISE: Contributions to the Understanding of Ischemia and Heart Failure among Women with No Obstructive Coronary Arteries.
Reviews in cardiovascular medicine.
24(3)
[DOI] 10.31083/j.rcm2403090.
[PMID] 39077501.
2023
Left ventricular ejection fraction and long-term outcomes in women presenting with signs and symptoms of ischaemia.
Heart (British Cardiac Society).
109(21):1624-1630
[DOI] 10.1136/heartjnl-2023-322494.
[PMID] 37316162.
2023
Long-Term Adverse Outcomes in Black Women With Ischemia and No Obstructive Coronary Artery Disease: A Study of the WISE (Women’s Ischemia Syndrome Evaluation) Cohort.
Circulation.
147(7):617-619
[DOI] 10.1161/CIRCULATIONAHA.122.063466.
[PMID] 36780383.
2023
Long-term Adverse Outcomes in Black Women With Obstructive Coronary Artery Disease: A Study of the Women’s Ischemia Syndrome Evaluation (WISE) Cohort.
The Canadian journal of cardiology.
39(11):1664-1666
[DOI] 10.1016/j.cjca.2023.08.010.
[PMID] 37897475.
2023
Longitudinal cardiac remodeling in collegiate American football players as assessed by echocardiography during their collegiate career.
Clinical cardiology.
46(9):1090-1096
[DOI] 10.1002/clc.24121.
[PMID] 37573574.
2023
Modifiable statin characteristics associated with potential statin-related prescribing cascades.
Pharmacotherapy.
43(12):1307-1316
[DOI] 10.1002/phar.2883.
[PMID] 37771303.
2023
Racial and Ethnic Differences in Cardiac Surveillance Evaluation of Patients Treated With Anthracycline-Based Chemotherapy.
Journal of the American Heart Association.
12(10)
[DOI] 10.1161/JAHA.122.027981.
[PMID] 37158063.
2023
Relationship between arm span to height ratio, aortic root diameter, and systolic blood pressure in collegiate athletes.
American heart journal plus : cardiology research and practice.
25
[DOI] 10.1016/j.ahjo.2022.100242.
[PMID] 38510494.
2023
Reprograming of transcriptional profile of colonic organoids from patients with high blood pressure by minocycline.
American heart journal plus : cardiology research and practice.
36
[DOI] 10.1016/j.ahjo.2023.100343.
[PMID] 38222308.
2023
Sex-Specific Effects of Blood Pressure Lowering Pharmacotherapy for the Prevention of Cardiovascular Disease: An Individual Participant-Level Data Meta-Analysis.
Hypertension (Dallas, Tex. : 1979).
80(11):2293-2302
[DOI] 10.1161/HYPERTENSIONAHA.123.21496.
[PMID] 37485657.
2023
Social Vulnerability Is Associated With Higher Rates of Hospitalizations and Amputations for Peripheral Arterial Disease.
The American journal of cardiology.
203:463-465
[DOI] 10.1016/j.amjcard.2023.07.063.
[PMID] 37542956.
2023
Symptom Presentation among Women with Suspected Ischemia and No Obstructive Coronary Artery Disease (INOCA).
Journal of clinical medicine.
12(18)
[DOI] 10.3390/jcm12185836.
[PMID] 37762777.
2023
The CardiAMP Cell Therapy for Heart Failure trial.
Texas Heart Institute journal.
50(5)
[DOI] 10.14503/THIJ-23-8242.
[PMID] 37881037.
2022
Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis.
Frontiers in physiology.
13
[DOI] 10.3389/fphys.2022.909870.
[PMID] 35812313.
2022
Blood pressure characteristics of collegiate female athletes: A call for more focused attention on young women’s health.
American heart journal plus : cardiology research and practice.
13
[DOI] 10.1016/j.ahjo.2022.100085.
[PMID] 38560086.
2022
Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis.
The lancet. Diabetes & endocrinology.
10(9):645-654
[DOI] 10.1016/S2213-8587(22)00172-3.
[PMID] 35878651.
2022
Body weight and physical fitness in women with ischaemic heart disease: does physical fitness contribute to our understanding of the obesity paradox in women?
European journal of preventive cardiology.
29(12):1608-1614
[DOI] 10.1093/eurjpc/zwac046.
[PMID] 35244151.
2022
Cold Pressor Testing and Sympathetic Nervous System Contribution to Ischemia with No Obstructive Coronary Artery Disease: Results from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Project.
American heart journal plus : cardiology research and practice.
13
[DOI] 10.1016/j.ahjo.2021.100080.
[PMID] 36262746.
2022
Concomitant coronary microvascular dysfunction and spontaneous coronary artery dissection resulting in ST-segment elevation myocardial infarction.
Journal of cardiology cases.
25(2):76-78
[DOI] 10.1016/j.jccase.2021.06.014.
[PMID] 35079302.
2022
Coronary microvascular dysfunction as a chronic inflammatory state: Is there a role for omega-3 fatty acid treatment?
American heart journal plus : cardiology research and practice.
13
[DOI] 10.1016/j.ahjo.2022.100098.
[PMID] 38560085.
2022
Coronary Microvascular Dysfunction in Patients with Non-Obstructive Coronary Arteries: Current Gaps and Future Directions.
Drugs.
82(3):241-250
[DOI] 10.1007/s40265-021-01667-y.
[PMID] 35092594.
2022
Critical role of the coronary microvasculature in heart disease: From pathologic driving force to “innocent” bystander.
American heart journal plus : cardiology research and practice.
22
[DOI] 10.1016/j.ahjo.2022.100215.
[PMID] 38558907.
2022
Dare to dream? Cell-based therapies for heart failure after DREAM-HF: Review and roadmap for future clinical study.
American heart journal plus : cardiology research and practice.
13
[DOI] 10.1016/j.ahjo.2022.100118.
[PMID] 38560073.
2022
Depression Symptom Patterns as Predictors of Metabolic Syndrome and Cardiac Events in Symptomatic Women with Suspected Myocardial Ischemia: The Women’s Ischemia Syndrome Evaluation (WISE and WISE-CVD) Projects.
Heart and mind (Mumbai, India).
6(4):254-261
[PMID] 36994354.
2022
Digital health intervention in patients with recent hospitalization for acute heart failure: A systematic review and meta-analysis of randomized trials.
International journal of cardiology.
359:46-53
[DOI] 10.1016/j.ijcard.2022.04.039.
[PMID] 35436558.
2022
Efficacy and Safety of MSC Cell Therapies for Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis.
Stem cells translational medicine.
11(7):688-703
[DOI] 10.1093/stcltm/szac032.
[PMID] 35640138.
2022
Evaluation of a Beta-Blocker-Edema-Loop Diuretic Prescribing Cascade: A Prescription Sequence Symmetry Analysis.
American journal of hypertension.
35(7):601-609
[DOI] 10.1093/ajh/hpac013.
[PMID] 35106529.
2022
Evaluation of the key prescription sequence symmetry analysis assumption using the calcium channel blocker: Loop diuretic prescribing cascade.
Pharmacoepidemiology and drug safety.
31(1):72-81
[DOI] 10.1002/pds.5362.
[PMID] 34553438.
2022
First and recurrent events in the ISCHEMIA trial: two sides of the same coin.
European heart journal.
43(2):150-152
[DOI] 10.1093/eurheartj/ehab603.
[PMID] 34514507.
2022
Gut Microbiome and Neuroinflammation in Hypertension.
Circulation research.
130(3):401-417
[DOI] 10.1161/CIRCRESAHA.121.319816.
[PMID] 35113664.
2022
Identification of a Gut Commensal That Compromises the Blood Pressure-Lowering Effect of Ester Angiotensin-Converting Enzyme Inhibitors.
Hypertension (Dallas, Tex. : 1979).
79(8):1591-1601
[DOI] 10.1161/HYPERTENSIONAHA.121.18711.
[PMID] 35538603.
2022
Intravenous administration of umbilical cord lining stem cells in left ventricular assist device recipient: Rationale and design of the uSTOP LVAD BLEED pilot study.
American heart journal plus : cardiology research and practice.
16
[DOI] 10.1016/j.ahjo.2022.100142.
[PMID] 38559284.
2022
Ischemia and no obstructive coronary arteries in patients with stable ischemic heart disease.
International journal of cardiology.
348:1-8
[DOI] 10.1016/j.ijcard.2021.12.013.
[PMID] 34902504.
2022
Ischemic Heart Disease in Young Women: JACC Review Topic of the Week.
Journal of the American College of Cardiology.
80(10):1014-1022
[DOI] 10.1016/j.jacc.2022.01.057.
[PMID] 36049799.
2022
Medicare Bundled Payment Policy on Anemia Care, Major Adverse Cardiovascular Events, and Mortality among Adults Undergoing Hemodialysis.
Clinical journal of the American Society of Nephrology : CJASN.
17(6):851-860
[DOI] 10.2215/CJN.14361121.
[PMID] 35589388.
2022
Microvascular Dysfunction as a Systemic Disease: A Review of the Evidence
The American journal of medicine.
135(9):1059-1068
[DOI] 10.1016/j.amjmed.2022.04.006.
[PMID] 35472396.
2022
Non-obstructive Plaque and Treatment of INOCA: More to Be Learned.
Current atherosclerosis reports.
24(9):681-687
[DOI] 10.1007/s11883-022-01044-4.
[PMID] 35781776.
2022
Our academic heritage from CR Conti-A lifetime committed to education and excellence.
Clinical cardiology.
45(11):1085-1088
[DOI] 10.1002/clc.23912.
[PMID] 36165103.
2022
Prognostic association of plasma NT-proBNP levels in patients with microvascular angina -A report from the international cohort study by COVADIS.
International journal of cardiology. Heart & vasculature.
43
[DOI] 10.1016/j.ijcha.2022.101139.
[PMID] 36338319.
2022
Recommendations for nomenclature and definition of cell products intended for human cardiovascular use.
Cardiovascular research.
118(11):2428-2436
[DOI] 10.1093/cvr/cvab270.
[PMID] 34387303.
2022
Relationship of Psychological Characteristics to Daily Life Ischemia: An Analysis From the National Heart, Lung, and Blood Institute Psychophysiological Investigations in Myocardial Ischemia.
Psychosomatic medicine.
84(3):359-367
[DOI] 10.1097/PSY.0000000000001044.
[PMID] 35067655.
2022
RNA Virus Gene Signatures Detected in Patients With Cardiomyopathy After Chemotherapy; A Pilot Study.
Frontiers in cardiovascular medicine.
9
[DOI] 10.3389/fcvm.2022.821162.
[PMID] 35360008.
2022
Sex-dimorphic gene effects on survival outcomes in people with coronary artery disease.
American heart journal plus : cardiology research and practice.
17
[DOI] 10.1016/j.ahjo.2022.100152.
[PMID] 35959094.
2022
Specialized Proresolving Mediators in Symptomatic Women With Coronary Microvascular Dysfunction (from the Women’s Ischemia Trial to Reduce Events in Nonobstructive CAD [WARRIOR] Trial).
The American journal of cardiology.
162:1-5
[DOI] 10.1016/j.amjcard.2021.09.015.
[PMID] 34728061.
2022
The Blood Pressure Lowering Treatment Trialists’ Collaboration: methodological clarifications of recent reports.
Journal of hypertension.
40(5):847-852
[DOI] 10.1097/HJH.0000000000003107.
[PMID] 35221323.
2022
Trans-myocardial omega-3 fatty acid gradient in coronary microvascular dysfunction.
American heart journal plus : cardiology research and practice.
22
[DOI] 10.1016/j.ahjo.2022.100213.
[PMID] 37377675.
2022
Ultra-high sensitivity cardiac troponin-I concentration and left ventricular structure and function in women with ischemia and no obstructive coronary artery disease.
American heart journal plus : cardiology research and practice.
13
[DOI] 10.1016/j.ahjo.2022.100115.
[PMID] 35784010.
2022
What Is the Role of Assessing Ischemia to Optimize Therapy and Outcomes for Patients with Stable Angina and Non-obstructed Coronary Arteries?
Cardiovascular drugs and therapy.
36(5):1027-1038
[DOI] 10.1007/s10557-021-07179-x.
[PMID] 33978865.
2021
A multiplexed ion-exchange membrane-based miRNA (MIX·miR) detection platform for rapid diagnosis of myocardial infarction.
Lab on a chip.
21(20):3876-3887
[DOI] 10.1039/d1lc00685a.
[PMID] 34546237.
2021
A Phase II study of autologous mesenchymal stromal cells and c-kit positive cardiac cells, alone or in combination, in patients with ischaemic heart failure: the CCTRN CONCERT-HF trial.
European journal of heart failure.
23(4):661-674
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2021
A Six-Day, Lifestyle-Based Immersion Program Mitigates Cardiovascular Risk Factors and Induces Shifts in Gut Microbiota, Specifically Lachnospiraceae, Ruminococcaceae, Faecalibacterium prausnitzii: A Pilot Study.
Nutrients.
13(10)
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2021
Acute Pulmonary Embolism During Pregnancy and Puerperium: National Trends and In-Hospital Outcomes.
Mayo Clinic proceedings.
96(8):2102-2113
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[PMID] 34144802.
2021
Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies.
Clinical pharmacology and therapeutics.
110(3):723-732
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2021
Anemia and Long-term cardiovascular outcomes in women with suspected ischemia – The Women’s Ischemia Syndrome Evaluation (WISE).
American heart journal plus : cardiology research and practice.
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2021
Angina relates to coronary flow in women with ischemia and no obstructive coronary artery disease.
International journal of cardiology.
333:35-39
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[PMID] 33662486.
2021
Antihypertensive medication adherence trends by sex and drug class: A pilot study.
American heart journal plus : cardiology research and practice.
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2021
Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis.
The Lancet. Oncology.
22(4):558-570
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2021
Aspirin in Primary Prevention: What Changed? A Critical Appraisal of Current Evidence.
The American journal of cardiology.
141:38-48
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[PMID] 33221264.
2021
Association of 1-Year Blood Pressure Variability With Long-term Mortality Among Adults With Coronary Artery Disease: A Post Hoc Analysis of a Randomized Clinical Trial.
JAMA network open.
4(4)
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2021
Association of coronary microvascular dysfunction and cardiac bridge integrator 1, a cardiomyocyte dysfunction biomarker.
Clinical cardiology.
44(11):1586-1593
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[PMID] 34528718.
2021
Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis.
Lancet (London, England).
398(10313):1803-1810
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2021
Blood pressure-lowering treatment for the prevention of cardiovascular events in patients with atrial fibrillation: An individual participant data meta-analysis.
PLoS medicine.
18(6)
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2021
Butyrate Regulates COVID-19-Relevant Genes in Gut Epithelial Organoids From Normotensive Rats.
Hypertension (Dallas, Tex. : 1979).
77(2):e13-e16
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2021
Cardiac Sympathetic Activity by 123I-Meta-Iodobenzylguanidine Imaging in Women With Coronary Microvascular Dysfunction: A Pilot Study.
JACC. Cardiovascular imaging.
14(9):1873-1875
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[PMID] 34147436.
2021
Clinical characteristics and prognosis of patients with microvascular angina: an international and prospective cohort study by the Coronary Vasomotor Disorders International Study (COVADIS) Group.
European heart journal.
42(44):4592-4600
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[PMID] 34038937.
2021
Clinical Safety Profile of Transendocardial Catheter Injection Systems: A Plea for Uniform Reporting.
Cardiovascular revascularization medicine : including molecular interventions.
22:100-108
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2021
Clinician engagement in the ADAPTABLE (Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-Term Effectiveness) trial.
Clinical trials (London, England).
18(4):449-456
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2021
Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease.
The New England journal of medicine.
384(21):1981-1990
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2021
Coronary atheroma burden predicts flow reserve in women with ischemia and nonobstructive coronary artery disease.
American heart journal plus : cardiology research and practice.
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2021
Coronary endothelial dysfunction appears to be a manifestation of a systemic process: A report from the Women’s Ischemia Syndrome Evaluation – Coronary Vascular Dysfunction (WISE-CVD) study.
PloS one.
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2021
Depression phenotype identified by using single nucleotide exact amplicon sequence variants of the human gut microbiome.
Molecular psychiatry.
26(8):4277-4287
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2021
Depressive hypertension: A proposed human endotype of brain/gut microbiome dysbiosis.
American heart journal.
239:27-37
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2021
Diagnostic Cardiovascular Imaging and Therapeutic Strategies in Pregnancy: JACC Focus Seminar 4/5.
Journal of the American College of Cardiology.
77(14):1813-1822
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2021
Distinct Gene Expression Profiles in Colonic Organoids from Normotensive and the Spontaneously Hypertensive Rats.
Cells.
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2021
Does Patient-Physician Gender Concordance Influence Patient Perceptions or Outcomes?
Journal of the American College of Cardiology.
77(8):1135-1138
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[PMID] 33632488.
2021
Effect of Antithrombotic Therapy on Clinical Outcomes in Outpatients With Clinically Stable Symptomatic COVID-19: The ACTIV-4B Randomized Clinical Trial.
JAMA.
326(17):1703-1712
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2021
Effectiveness of sacubitril/valsartan versus aldosterone antagonists in heart failure with reduced ejection fraction: A retrospective cohort study.
Pharmacotherapy.
41(9):710-721
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2021
Efficacy of Ranolazine for Treatment of Coronary Microvascular Dysfunction-A Systematic Review and Meta-analysis of Randomized Trials.
CJC open.
3(1):101-108
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2021
Emerging role of machine learning in cardiovascular disease investigation and translations.
American heart journal plus : cardiology research and practice.
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2021
Epicardial delivery of XC001 gene therapy for refractory angina coronary treatment (The EXACT Trial): Rationale, design, and clinical considerations.
American heart journal.
241:38-49
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2021
Erratum to “Cardiovascular Considerations for the Internist and Hospitalist in the COVID-19 Era” AmJMed, 133(11); 1254-1261.
The American journal of medicine.
134(4)
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2021
Functional heart recovery in an adult mammal, the spiny mouse.
International journal of cardiology.
338:196-203
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[PMID] 34126132.
2021
Impact of a preventive cardiology clinic focusing on lifestyle and nutrition counseling: A pilot analysis.
American heart journal plus : cardiology research and practice.
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2021
Insights to advance our management of myocardial ischemia: From obstructive epicardial disease to functional coronary alterations.
American heart journal plus : cardiology research and practice.
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2021
Lactate Dehydrogenase B and Pyruvate Oxidation Pathway Associated With Carfilzomib-Related Cardiotoxicity in Multiple Myeloma Patients: Result of a Multi-Omics Integrative Analysis.
Frontiers in cardiovascular medicine.
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2021
Left ventricular circumferential strain and coronary microvascular dysfunction: A report from the Women’s Ischemia Syndrome Evaluation Coronary Vascular Dysfunction (WISE-CVD) Project.
International journal of cardiology.
327:25-30
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2021
Management of Cardiovascular Disease in Kidney Disease Study: Rationale and Design.
American journal of nephrology.
52(1):36-44
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2021
Management of Women With Acquired Cardiovascular Disease From Pre-Conception Through Pregnancy and Postpartum: JACC Focus Seminar 3/5.
Journal of the American College of Cardiology.
77(14):1799-1812
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2021
Management of Women With Congenital or Inherited Cardiovascular Disease From Pre-Conception Through Pregnancy and Postpartum: JACC Focus Seminar 2/5.
Journal of the American College of Cardiology.
77(14):1778-1798
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[PMID] 33832605.
2021
Maternal Stroke
Circulation.
143(7):727-738
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2021
Newly diagnosed cardiovascular disease in patients treated with immune checkpoint inhibitors: a retrospective analysis of patients at an academic tertiary care center.
Cardio-oncology (London, England).
7(1)
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2021
Peak Systolic Blood Pressure During the Exercise Test: Reference Values by Sex and Age and Association With Mortality.
Hypertension (Dallas, Tex. : 1979).
77(6):1906-1914
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2021
Perfusion, cryopreservation, and nanowarming of whole hearts using colloidally stable magnetic cryopreservation agent solutions.
Science advances.
7(2)
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2021
Peripheral Blood Biomarkers Associated With Improved Functional Outcome in Patients With Chronic Left Ventricular Dysfunction: A Biorepository Evaluation of the FOCUS-CCTRN Trial.
Frontiers in cardiovascular medicine.
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2021
Phytoestrogen blood levels and adverse outcomes in women with suspected ischemic heart disease.
European journal of clinical nutrition.
75(5):829-835
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2021
Point of care, bone marrow mononuclear cell therapy in ischemic heart failure patients personalized for cell potency: 12-month feasibility results from CardiAMP heart failure roll-in cohort.
International journal of cardiology.
326:131-138
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2021
Potential of Minocycline for Treatment of Resistant Hypertension.
The American journal of cardiology.
156:147-149
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[PMID] 34348841.
2021
Preparticipation Cardiac Evaluation Findings in a Cohort of Collegiate Female Athletes.
The American journal of cardiology.
140:134-139
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[PMID] 33144161.
2021
Prior Oral Contraceptive Use and Longer Term Mortality Outcomes in Women with Suspected Ischemic Heart Disease.
Journal of women's health (2002).
30(3):377-384
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2021
Rationale and design of the Women’s Ischemia Trial to Reduce Events in Nonobstructive CAD (WARRIOR) trial.
American heart journal.
237:90-103
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2021
Relationship between coronary function testing and migraine: results from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction project.
Vessel plus.
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2021
Reply to “Angiotensin-converting enzyme 2, sex differences, and COVID-19: The missing link”.
International journal of cardiology.
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2021
Reproductive lifespan and incident stroke risk among post-menopausal women: Is it time for sex-specific risk prediction tools?
International journal of cardiology.
328:218-219
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[PMID] 33359280.
2021
Risk factors for heart failure in women with ischemia and no obstructive coronary artery disease.
American heart journal plus : cardiology research and practice.
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2021
Sex and gender differences in COVID-19: More to be learned!
American heart journal plus : cardiology research and practice.
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2021
Sex Differences, Aspirin, and Primary Prevention.
The American journal of medicine.
134(1):9-10
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2021
Somatic Versus Cognitive Depressive Symptoms as Predictors of Coronary Artery Disease among Women with Suspected Ischemia: The Women’s Ischemia Syndrome Evaluation.
Heart and mind (Mumbai, India).
5(4):112-118
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2021
Syndrome of Nonobstructive Coronary Artery Diseases: A Comprehensive Overview of Open Artery Ischemia.
The American journal of medicine.
134(11):1321-1329
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[PMID] 34343507.
2021
The Clinical Spectrum of Myocardial Infarction and Ischemia With Nonobstructive Coronary Arteries in Women.
JACC. Cardiovascular imaging.
14(5):1053-1062
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2021
The role of a comprehensive two-step diagnostic evaluation to unravel the pathophysiology of MINOCA: A review.
International journal of cardiology.
336:1-7
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2021
Women and atrial fibrillation.
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32(10):2793-2807
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2020
A Cardio-Obstetric Approach to Management of the Complex Pregnant Cardiac Patient.
JACC. Case reports.
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2020
ACE2 (Angiotensin-Converting Enzyme 2) in Cardiopulmonary Diseases: Ramifications for the Control of SARS-CoV-2.
Hypertension (Dallas, Tex. : 1979).
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2020
Acute Stroke During Pregnancy and Puerperium.
Journal of the American College of Cardiology.
75(2):180-190
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2020
Adverse Pregnancy Outcomes Are Associated with Reduced Coronary Flow Reserve in Women With Signs and Symptoms of Ischemia Without Obstructive Coronary Artery Disease: A Report from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Study.
Journal of women's health (2002).
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2020
Allogeneic Mesenchymal Cell Therapy in Anthracycline-Induced Cardiomyopathy Heart Failure Patients: The CCTRN SENECA Trial.
JACC. CardioOncology.
2(4):581-595
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2020
Altered Gut Microbiome Profile in Patients With Pulmonary Arterial Hypertension.
Hypertension (Dallas, Tex. : 1979).
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2020
Angina Hospitalization Rates in Women With Signs and Symptoms of Ischemia But no Obstructive Coronary Artery Disease: A Report from the WISE (Women’s Ischemia Syndrome Evaluation) Study.
Journal of the American Heart Association.
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2020
Assessment of Vascular Dysfunction in Patients Without Obstructive Coronary Artery Disease: Why, How, and When.
JACC. Cardiovascular interventions.
13(16):1847-1864
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2020
Association of Factor V Leiden With Subsequent Atherothrombotic Events
Circulation.
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2020
Attended vs unattended systolic blood pressure measurement: A randomized comparison in patients with cardiovascular disease.
Journal of clinical hypertension (Greenwich, Conn.).
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2020
Cardiac stem cell therapy among Clinics of Uncertain Regulatory Status (COURS): under-regulated, under-observed, incompletely understood.
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2020
Cardiovascular Considerations for the Internist and Hospitalist in the COVID-19 Era.
The American journal of medicine.
133(11):1254-1261
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2020
Cell Therapy Strategies With No Safety Concerns and Demonstrated Benefits Warrant Study.
Circulation journal : official journal of the Japanese Circulation Society.
84(11):2120-2121
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2020
Commentary – The ISCHEMIA trial.
International journal of cardiology.
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2020
Coronary Vascular Function and Cardiomyocyte Injury
Arteriosclerosis, Thrombosis, and Vascular Biology.
40(12):3015-3021
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2020
Design, methodology and baseline characteristics of the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD).
American heart journal.
220:224-236
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2020
Even “WISE-R?”-an Update on the NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation.
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Heart failure with preserved ejection fraction: Similarities and differences between women and men.
International journal of cardiology.
304:101-108
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2020
Immune Dysregulation in HFpEF: A Target for Mesenchymal Stem/Stromal Cell Therapy.
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International journal of cardiology. Heart & vasculature.
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Invasive Functional Assessment in Patients With Angina and Coronary Microvascular Dysfunction: A Plea for More.
Journal of the American College of Cardiology.
75(20):2550-2552
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2020
Left ventricular mass and myocardial scarring in women with hypertensive disorders of pregnancy.
Open heart.
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2020
Maternal Treatment With Captopril Persistently Alters Gut-Brain Communication and Attenuates Hypertension of Male Offspring.
Hypertension (Dallas, Tex. : 1979).
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2020
Myocardial Infarction and Persistent Angina With No Obstructive Coronary Artery Disease.
JACC. Case reports.
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2020
Myocardial ischemia: From disease to syndrome.
International journal of cardiology.
314:32-35
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2020
N-Terminal pro-B-type natriuretic peptide and coronary microvascular dysfunction in women with preserved ejection fraction: A report from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) study.
PloS one.
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2020
Not typical angina and mortality in women with obstructive coronary artery disease: Results from the Women’s Ischemic Syndrome Evaluation study (WISE).
International journal of cardiology. Heart & vasculature.
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Optimal systolic blood pressure and reduced long-term mortality in older hypertensive women with prior coronary events – An analysis from INVEST☆.
International Journal of Cardiology. Hypertension.
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2020
Oxidative Stress Is Associated With Diastolic Dysfunction in Women With Ischemia With No Obstructive Coronary Artery Disease.
Journal of the American Heart Association.
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Predicted Versus Observed Major Adverse Cardiac Event Risk in Women With Evidence of Ischemia and No Obstructive Coronary Artery Disease: A Report From WISE (Women’s Ischemia Syndrome Evaluation).
Journal of the American Heart Association.
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Psychological stress, cardiac symptoms, and cardiovascular risk in women with suspected ischaemia but no obstructive coronary disease.
Stress and health : journal of the International Society for the Investigation of Stress.
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Redefining Resistant Hypertension: A Comparison of Cardiovascular Risk Associated With the 2018 Versus 2008 American Heart Association Definitions for Resistant Hypertension.
Circulation. Cardiovascular quality and outcomes.
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2020
Reply: Factors Associated With Acute Stroke During Pregnancy and Puerperium.
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2020
Resting coronary velocity and myocardial performance in women with impaired coronary flow reserve: Results from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) study.
International journal of cardiology.
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2020
Risk and Blood Pressure Control Rates Across the Spectrum of Coronary Artery Disease in Hypertensive Women: An Analysis from The INternational VErapamil SR-Trandolapril STudy (INVEST).
Journal of women's health (2002).
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Statin Use for Atherosclerotic Cardiovascular Disease Prevention Among Sexual Minority Adults
Journal of the American Heart Association.
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2020
Summary of Updated Recommendations for Primary Prevention of Cardiovascular Disease in Women: JACC State-of-the-Art Review.
Journal of the American College of Cardiology.
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2020
Temporal Trends in Angina, Myocardial Perfusion, and Left Ventricular Remodeling in Women With No Obstructive Coronary Artery Disease Over 1-Year Follow-Up: Results From WISE-CVD.
Journal of the American Heart Association.
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2020
Thiazide Exposure and Cardiovascular Risk in Type 2 Diabetes Mellitus: A Point of Clarification.
Hypertension (Dallas, Tex. : 1979).
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Transcriptomic signature of gut microbiome-contacting cells in colon of spontaneously hypertensive rats.
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2020
What is the Real Message of the ISCHEMIA Trial from a Clinician’s Perspective?
European cardiology.
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[PMID] 32983263.
2020
Why are women better protected from COVID-19: Clues for men? Sex and COVID-19.
International journal of cardiology.
315:105-106
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[PMID] 32418736.
2020
Would Repurposing Minocycline Alleviate Neurologic Manifestations of COVID-19?
Frontiers in neuroscience.
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[PMID] 33117121.
2019
Adenosine vs Regadenoson Pharmacologic Stress Differs in Women with Suspected Coronary Microvascular Dysfunction: A Report from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) Study.
Cardiovascular disorder and medicine.
2019
[DOI] 10.31487/j.cdm.2019.01.01.
[PMID] 36913201.
2019
Advances in small-molecule therapy for managing angina pectoris in the elderly.
Expert opinion on pharmacotherapy.
20(12):1471-1481
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[PMID] 31107109.
2019
Age at Menarche and Risk of Cardiovascular Disease Outcomes: Findings From the National Heart Lung and Blood Institute-Sponsored Women’s Ischemia Syndrome Evaluation.
Journal of the American Heart Association.
8(12)
[DOI] 10.1161/JAHA.119.012406.
[PMID] 31165670.
2019
Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.
Circulation. Genomic and precision medicine.
12(4)
[DOI] 10.1161/CIRCGEN.119.002471.
[PMID] 30897348.
2019
Complementary Embryonic and Adult Cell Populations Enhance Myocardial Repair in Rat Myocardial Injury Model.
Stem cells international.
2019
[DOI] 10.1155/2019/3945850.
[PMID] 31781239.
2019
First-in-Man Study of a Cardiac Extracellular Matrix Hydrogel in Early and Late Myocardial Infarction Patients.
JACC. Basic to translational science.
4(6):659-669
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[PMID] 31709316.
2019
Gender in cardiovascular medicine: chest pain and coronary artery disease.
European Heart Journal.
40(47):3819-3826
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[PMID] 31713592.
2019
Genome-wide association analysis of common genetic variants of resistant hypertension
The pharmacogenomics journal.
19(3):295-304
[DOI] 10.1038/s41397-018-0049-x.
[PMID] 30237584.
2019
Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies).
Journal of the American Heart Association.
8(16)
[DOI] 10.1161/JAHA.119.013115.
[PMID] 31423876.
2019
Heart Failure With Preserved Ejection Fraction: Is Ischemia Due to Coronary Microvascular Dysfunction a Mechanistic Factor?
The American journal of medicine.
132(6):692-697
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[PMID] 30684452.
2019
Impact of Abnormal Coronary Reactivity on Long-Term Clinical Outcomes in Women.
Journal of the American College of Cardiology.
73(6):684-693
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[PMID] 30765035.
2019
Impaired Autonomic Nervous System-Microbiome Circuit in Hypertension.
Circulation research.
125(1):104-116
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[PMID] 31219753.
2019
Incidence, prevalence, and predictors of treatment-resistant hypertension with intensive blood pressure lowering.
Journal of clinical hypertension (Greenwich, Conn.).
21(6):825-834
[DOI] 10.1111/jch.13550.
[PMID] 31066177.
2019
Investigating the stratified efficacy and safety of pharmacological blood pressure-lowering: an overall protocol for individual patient-level data meta-analyses of over 300 000 randomised participants in the new phase of the Blood Pressure Lowering Treatment Trialists’ Collaboration (BPLTTC).
BMJ open.
9(5)
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[PMID] 31123005.
2019
Late sodium channel blockade improves angina and myocardial perfusion in patients with severe coronary microvascular dysfunction: Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction ancillary study.
International journal of cardiology.
276:8-13
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[PMID] 30293664.
2019
Left ventricular concentric remodelling and functional impairment in women with ischaemia with no obstructive coronary artery disease and intermediate coronary flow reserve: a report from the WISE-CVD study.
European heart journal. Cardiovascular Imaging.
20(8):875-882
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[PMID] 30904924.
2019
Magnitude of and Characteristics Associated With the Treatment of Calcium Channel Blocker-Induced Lower-Extremity Edema With Loop Diuretics.
JAMA network open.
2(12)
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[PMID] 31880802.
2019
Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization.
European heart journal.
40(29):2455-2462
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[PMID] 30608528.
2019
Medical Therapy for Heart Failure Caused by Ischemic Heart Disease.
Circulation research.
124(11):1520-1535
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2019
Microglial Cells Impact Gut Microbiota and Gut Pathology in Angiotensin II-Induced Hypertension.
Circulation research.
124(5):727-736
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[PMID] 30612527.
2019
Migraine Headache: An Under-Appreciated Risk Factor for Cardiovascular Disease in Women.
Journal of the American Heart Association.
8(22)
[DOI] 10.1161/JAHA.119.014546.
[PMID] 31707945.
2019
Novel Self-Report Tool for Cardiovascular Risk Assessment.
Journal of the American Heart Association.
8(24)
[DOI] 10.1161/JAHA.119.014123.
[PMID] 31818214.
2019
Prevalence of Coronary Endothelial and Microvascular Dysfunction in Women with Symptoms of Ischemia and No Obstructive Coronary Artery Disease Is Confirmed by a New Cohort: The NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD).
Journal of interventional cardiology.
2019
[DOI] 10.1155/2019/7169275.
[PMID] 31772544.
2019
Sex and Race/Ethnicity Differences in Atrial Fibrillation.
Journal of the American College of Cardiology.
74(22):2812-2815
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[PMID] 31779796.
2019
Sex Differences in Cardiovascular Disease and Cognitive Impairment: Another Health Disparity for Women?
Journal of the American Heart Association.
8(19)
[DOI] 10.1161/JAHA.119.013154.
[PMID] 31549581.
2019
Subsequent Event Risk in Individuals With Established Coronary Heart Disease.
Circulation. Genomic and precision medicine.
12(4)
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[PMID] 30896328.
2019
Sustained Captopril-Induced Reduction in Blood Pressure Is Associated With Alterations in Gut-Brain Axis in the Spontaneously Hypertensive Rat.
Journal of the American Heart Association.
8(4)
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[PMID] 30755073.
2019
β2 -Adrenergic Receptor Gene Affects the Heart Rate Response of β-Blockers: Evidence From 3 Clinical Studies.
Journal of clinical pharmacology.
59(11):1462-1470
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2018
Author Correction: Circulating Biomarkers to Identify Responders in Cardiac Cell therapy.
Scientific reports.
8(1)
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[PMID] 29511207.
2018
Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure: A meta-analysis of individual participant data.
PLoS medicine.
15(3)
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[PMID] 29558462.
2018
Extent of coronary atherosclerosis and arterial remodelling in women: the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation.
Cardiovascular diagnosis and therapy.
8(4):405-413
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[PMID] 30214855.
2018
Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes.
The pharmacogenomics journal.
18(1):106-112
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[PMID] 27670767.
2018
Gut microbiota and serum metabolite differences in African Americans and White Americans with high blood pressure.
International journal of cardiology.
271:336-339
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[PMID] 30049487.
2018
High sensitivity cardiac troponin T and I and risk stratification of patients with stable CHD: Is it time to incorporate this in routine clinical practice?
International journal of cardiology.
250:266-267
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[PMID] 29169758.
2018
Hypertension Across a Woman’s Life Cycle.
Journal of the American College of Cardiology.
71(16):1797-1813
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[PMID] 29673470.
2018
Hypertension in Florida: Data From the OneFlorida Clinical Data Research Network.
Preventing chronic disease.
15
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2018
Hypertension in pregnancy: Taking cues from pathophysiology for clinical practice.
Clinical cardiology.
41(2):220-227
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[PMID] 29485737.
2018
Imbalance of gut microbiome and intestinal epithelial barrier dysfunction in patients with high blood pressure.
Clinical science (London, England : 1979).
132(6):701-718
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2018
Increased human intestinal barrier permeability plasma biomarkers zonulin and FABP2 correlated with plasma LPS and altered gut microbiome in anxiety or depression.
Gut.
67(8):1555-1557
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[PMID] 28814485.
2018
Intensive blood pressure lowering reduces adverse cardiovascular outcomes among patients with high-normal glucose: An analysis from the Systolic Blood Pressure Intervention Trial database.
Journal of clinical hypertension (Greenwich, Conn.).
20(4):620-624
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[PMID] 29532983.
2018
Intracoronary Bolus Injection Versus Intravenous Infusion of Adenosine for Assessment of Coronary Flow Velocity Reserve in Women With Signs and Symptoms of Myocardial Ischemia and No Obstructive Coronary Artery Disease.
JACC. Cardiovascular interventions.
11(20):2125-2127
[DOI] 10.1016/j.jcin.2018.07.052.
[PMID] 30336817.
2018
Ischemia and No Obstructive Coronary Artery Disease ( INOCA ): What Is the Risk?
Journal of the American Heart Association.
7(17)
[DOI] 10.1161/JAHA.118.008868.
[PMID] 30371178.
2018
Long-term mortality and estimated functional capacity among women with symptoms of ischemic heart disease: From the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation.
American heart journal.
206:123-126
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[PMID] 30237012.
2018
Maladaptive left ventricular remodeling in women: An analysis from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction study.
International journal of cardiology.
268:230-235
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[PMID] 30041793.
2018
Mortality implications of lower DBP with lower achieved systolic pressures in coronary artery disease: long-term mortality results from the INternational VErapamil-trandolapril STudy US cohort.
Journal of hypertension.
36(2):419-427
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[PMID] 28938338.
2018
Myocardial Scar Is Prevalent and Associated With Subclinical Myocardial Dysfunction in Women With Suspected Ischemia But No Obstructive Coronary Artery Disease: From the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Study.
Circulation.
137(8):874-876
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[PMID] 29459474.
2018
Not All Stem Cells Are Created Equal.
Circulation research.
123(8):944-946
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[PMID] 30355037.
2018
Optimal medical treatment of hypertension in patients with coronary artery disease.
Expert review of cardiovascular therapy.
16(11):815-823
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[PMID] 30295548.
2018
Optimal Systolic Blood Pressure Target in Resistant and Non-Resistant Hypertension: A Pooled Analysis of Patient-Level Data from SPRINT and ACCORD.
The American journal of medicine.
131(12):1463-1472.e7
[DOI] 10.1016/j.amjmed.2018.08.005.
[PMID] 30142317.
2018
Prevalence, Causes, and Predictors of 30-Day Readmissions Following Hospitalization With Acute Myocardial Infarction Complicated By Cardiogenic Shock: Findings From the 2013-2014 National Readmissions Database.
Journal of the American Heart Association.
7(6)
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2018
Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit+ Cardiac Stem Cells As Regenerative Therapy for Heart Failure).
Circulation research.
122(12):1703-1715
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[PMID] 29703749.
2018
Rationale and Design of the SENECA (StEm cell iNjECtion in cAncer survivors) Trial.
American heart journal.
201:54-62
[DOI] 10.1016/j.ahj.2018.02.009.
[PMID] 29910056.
2018
Regenerative Medicine in the State of Florida: Letter Outlining the Florida Organization for Regenerative Medicine.
Stem cells translational medicine.
7(7):511-512
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[PMID] 30403444.
2018
The CardiAMP Heart Failure trial: A randomized controlled pivotal trial of high-dose autologous bone marrow mononuclear cells using the CardiAMP cell therapy system in patients with post-myocardial infarction heart failure: Trial rationale and study design.
American heart journal.
201:141-148
[DOI] 10.1016/j.ahj.2018.03.016.
[PMID] 29803986.
2018
The gut microbiota and the brain-gut-kidney axis in hypertension and chronic kidney disease.
Nature reviews. Nephrology.
14(7):442-456
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[PMID] 29760448.
2018
The Reply.
The American journal of medicine.
131(2)
[DOI] 10.1016/j.amjmed.2017.10.025.
[PMID] 29362110.
2018
TIME Trial: Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis.
Circulation research.
122(3):479-488
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2018
Unanticipated Cardiotoxicity Associated with Targeted Anticancer Therapy in Patients with Hematologic Malignancies Patients: Natural History and Risk Factors.
Cardiovascular toxicology.
18(2):184-191
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[PMID] 29022233.
2018
Why names matter for women: MINOCA/INOCA (myocardial infarction/ischemia and no obstructive coronary artery disease).
Clinical cardiology.
41(2):185-193
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[PMID] 29498752.
2017
Acetylcholine versus cold pressor testing for evaluation of coronary endothelial function.
PloS one.
12(2)
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[PMID] 28207868.
2017
Advancements in pharmacotherapy for angina.
Expert opinion on pharmacotherapy.
18(5):457-469
[DOI] 10.1080/14656566.2017.1303483.
[PMID] 28264619.
2017
Aortic flow conditions predict ejection efficiency in the NHLBI-Sponsored Women’s Ischemia Syndrome Evaluation (WISE).
Cardiovascular diagnosis and therapy.
7(3):288-295
[DOI] 10.21037/cdt.2017.03.07.
[PMID] 28567354.
2017
Blood pressure, heart rate, and double product: lessons learned from Japan.
Journal of hypertension.
35(9):1785-1786
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[PMID] 28767488.
2017
Cardiac Cell Therapy Evolving From Complex to Straightforward: Enabling Adoption and Affordability.
Circulation research.
121(10):1116-1118
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2017
Cardiovascular safety of NSAIDs: Additional insights after PRECISION and point of view.
Clinical cardiology.
40(12):1352-1356
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[PMID] 29247518.
2017
Circulating Biomarkers to Identify Responders in Cardiac Cell therapy.
Scientific reports.
7(1)
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[PMID] 28667255.
2017
Cold Pressor Stress Cardiac Magnetic Resonance Myocardial Flow Reserve Is Not Useful for Detection of Coronary Endothelial Dysfunction in Women with Signs and Symptoms of Ischemia and No Obstructive CAD.
PloS one.
12(1)
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[PMID] 28081214.
2017
Daily Activity Measured With Wearable Technology as a Novel Measurement of Treatment Effect in Patients With Coronary Microvascular Dysfunction: Substudy of a Randomized Controlled Crossover Trial.
JMIR research protocols.
6(12)
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[PMID] 29263019.
2017
Effect of Low-Furanocoumarin Hybrid Grapefruit Juice Consumption on Midazolam Pharmacokinetics.
Journal of clinical pharmacology.
57(3):305-311
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[PMID] 27503364.
2017
Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).
Circulation.
135(15):1417-1428
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[PMID] 28209728.
2017
Fertility Therapy and Long-Term Cardiovascular Risk: Raising More Questions Than Answers?
Journal of the American College of Cardiology.
70(10):1214-1215
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[PMID] 28859783.
2017
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.
Nature genetics.
49(7):1113-1119
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[PMID] 28530674.
2017
Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.
Journal of the American Heart Association.
6(11)
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[PMID] 29097388.
2017
Gut Microbiota: Potential for a Unifying Hypothesis for Prevention and Treatment of Hypertension.
Circulation research.
120(11):1724-1726
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2017
Hypertension-Linked Pathophysiological Alterations in the Gut.
Circulation research.
120(2):312-323
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[PMID] 27799253.
2017
Identification of cardiovascular risk factors associated with bone marrow cell subsets in patients with STEMI: a biorepository evaluation from the CCTRN TIME and LateTIME clinical trials.
Basic research in cardiology.
112(1)
[PMID] 27882430.
2017
Inflammatory biomarkers as predictors of heart failure in women without obstructive coronary artery disease: A report from the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE).
PloS one.
12(5)
[DOI] 10.1371/journal.pone.0177684.
[PMID] 28542263.
2017
Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging.
Journal of the American Medical Directors Association.
18(9):810.e1-810.e4
[DOI] 10.1016/j.jamda.2017.05.018.
[PMID] 28676292.
2017
Ischemia and No Obstructive Coronary Artery Disease (INOCA): Developing Evidence-Based Therapies and Research Agenda for the Next Decade.
Circulation.
135(11):1075-1092
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[PMID] 28289007.
2017
Menopausal symptoms and cardiovascular disease mortality in the Women’s Ischemia Syndrome Evaluation (WISE).
Menopause (New York, N.Y.).
24(2):126-132
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[PMID] 27676638.
2017
Migraine Headache and Long-Term Cardiovascular Outcomes: An Extended Follow-Up of the Women’s Ischemia Syndrome Evaluation.
The American journal of medicine.
130(6):738-743
[DOI] 10.1016/j.amjmed.2016.12.028.
[PMID] 28109970.
2017
Myocardial tissue deformation is reduced in subjects with coronary microvascular dysfunction but not rescued by treatment with ranolazine.
Clinical cardiology.
40(5):300-306
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2017
Peripheral Blood Cytokine Levels After Acute Myocardial Infarction: IL-1β- and IL-6-Related Impairment of Bone Marrow Function.
Circulation research.
120(12):1947-1957
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[PMID] 28490433.
2017
Quality and Equitable Health Care Gaps for Women: Attributions to Sex Differences in Cardiovascular Medicine.
Journal of the American College of Cardiology.
70(3):373-388
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[PMID] 28705320.
2017
Report of the National Heart, Lung, and Blood Institute Working Group on the Role of Microbiota in Blood Pressure Regulation: Current Status and Future Directions.
Hypertension (Dallas, Tex. : 1979).
[DOI] 10.1161/HYPERTENSIONAHA.117.09699.
[PMID] 28760940.
2017
Resistant Hypertension: Mechanisms and Treatment.
Current hypertension reports.
19(7)
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[PMID] 28597403.
2017
Sudden Cardiac Death in Women With Suspected Ischemic Heart Disease, Preserved Ejection Fraction, and No Obstructive Coronary Artery Disease: A Report From the Women’s Ischemia Syndrome Evaluation Study.
Journal of the American Heart Association.
6(8)
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[PMID] 28862961.
2017
Systolic blood pressure target: Have we identified the optimal target yet?
Journal of public health and emergency.
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2017
Ten-Year Mortality in the WISE Study (Women’s Ischemia Syndrome Evaluation).
Circulation. Cardiovascular quality and outcomes.
10(12)
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[PMID] 29217675.
2017
The Athena trials: Autologous adipose-derived regenerative cells for refractory chronic myocardial ischemia with left ventricular dysfunction.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.
89(2):169-177
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[PMID] 27148802.
2017
The Gut, Its Microbiome, and Hypertension.
Current hypertension reports.
19(4)
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2017
Typical angina is associated with greater coronary endothelial dysfunction but not abnormal vasodilatory reserve.
Clinical cardiology.
40(10):886-891
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[PMID] 28605043.
2016
A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve.
European heart journal.
37(19):1504-13
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[PMID] 26614823.
2016
An injectable capillary-like microstructured alginate hydrogel improves left ventricular function after myocardial infarction in rats.
International journal of cardiology.
220:149-54
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[PMID] 27379917.
2016
Angiotensin-converting enzyme 2 inhibits high-mobility group box 1 and attenuates cardiac dysfunction post-myocardial ischemia.
Journal of molecular medicine (Berlin, Germany).
94(1):37-49
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2016
Association between High Endocardial Unipolar Voltage and Improved Left Ventricular Function in Patients with Ischemic Cardiomyopathy.
Texas Heart Institute journal.
43(4):291-6
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2016
Autologous CD34+ Cell Therapy for Refractory Angina: 2-Year Outcomes From the ACT34-CMI Study.
Cell transplantation.
25(9):1701-1711
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2016
Bone marrow cell characteristics associated with patient profile and cardiac performance outcomes in the LateTIME-Cardiovascular Cell Therapy Research Network (CCTRN) trial.
American heart journal.
179:142-50
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2016
Brain-Gut-Bone Marrow Axis: Implications for Hypertension and Related Therapeutics.
Circulation research.
118(8):1327-36
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2016
Cardiovascular Disease and 10-Year Mortality in Postmenopausal Women with Clinical Features of Polycystic Ovary Syndrome.
Journal of women's health (2002).
25(9):875-81
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2016
CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril.
European journal of clinical pharmacology.
72(6):681-7
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2016
Circulating progenitor cells and coronary microvascular dysfunction: Results from the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation – Coronary Vascular Dysfunction Study (WISE-CVD).
Atherosclerosis.
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Correction: Effects of Verapamil SR and Atenolol on 24-Hour Blood Pressure and Heart Rate in Hypertension Patients with Coronary Artery Disease: An International Verapamil SR-Trandolapril Ambulatory Monitoring Substudy.
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Identification of Bone Marrow Cell Subpopulations Associated With Improved Functional Outcomes in Patients With Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation of the FOCUS-CCTRN Trial.
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A Pharmacogenomic Genome-Wide Association Study (Gwas) for New Onset Diabetes (Nod) in the International Verapamil Sr-Trandolapril Study (Invest)
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A Pharmacogenomic Genome-Wide Association Study (Gwas) for New Onset Diabetes (Nod) in the International Verapamil Sr-Trandolapril Study (Invest)
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A Pharmacogenomic Genome-Wide Association Study for Adverse Cardiovascular Outcomes in the International Verapamil Sr-Trandolapril Study (Invest)
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Atp2B1 Locus Is Associated With Resistant Hypertension in the International Verapamil Sr Tandolapril Study-Genetic Substudy (Investgenes)
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Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes.
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The Vascular Biology Working Group Twentieth Anniversary
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Adverse outcomes among women presenting with signs and symptoms of ischemia and no obstructive coronary artery disease: findings from the National Heart, Lung, and Blood Institute-sponsored Women’s Ischemia Syndrome Evaluation (WISE) angiographic core laboratory.
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Diminazene aceturate enhances angiotensin-converting enzyme 2 activity and attenuates ischemia-induced cardiac pathophysiology.
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An Injectable Acellular Capillary Hydrogel Improves Left Ventricular Function After Myocardial Infarction
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